Chemistry of Natural Compounds

, Volume 18, Issue 6, pp 738–741 | Cite as

Synthesis of N-alkyl- and N-(β-hydroxyalkyl)-2-(acylmethylthio)benzimidazoles and their properties

  • A. N. Krasovskii
  • A. B. Roman
  • M. A. Klyuev
  • T. I. Kalmazan
  • I. I. Soroka
  • S. M. Klyuev
Article
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Abstract

N-alkyl- and N-(β-hydroxyalkyl)-2-(acylmethylthio)benzimidazoles have been obtained by the reaction of N-alkyl- and N-(β-hydroxyalkyl)benzimidazoline-2-thiones with α-haloketones. The structures of the substances synthesized have been confirmed by IR, PMR, and mass spectra. The biological properties of the compounds obtained have been studied.

Keywords

Benzimidazole DMFA Methylbenzimidazole Benzimidazole Moiety Chloroacetone 

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Copyright information

© Plenum Publishing Corporation 1983

Authors and Affiliations

  • A. N. Krasovskii
  • A. B. Roman
  • M. A. Klyuev
  • T. I. Kalmazan
  • I. I. Soroka
  • S. M. Klyuev

There are no affiliations available

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