The cochlear and cerebral blood flow was studied in rabbits with the microsphere method before and 15 min after i.v. administration of ethanol. In a series of control experiments only saline was injected.
No alteration was measured in the cochlear and cerebral blood flow after the administration of saline, whereas both cochlear and cerebral blood flow showed an increase after ethanol administration. The results are discussed in relation to changes in serum osmolality and hearing in patients with Menière's disease.
Cochlear blood flow Microspheres Ethanol
This is a preview of subscription content, log in to check access.
Alm A, Bill A (1972) The oxygen supply to the retina. II. Effects of pressure on uveal and retinal blood flow in cats. A study with labelled microspheres including flow determinations in brain and some other tissues. Acta Physiol Scand 84: 306CrossRefGoogle Scholar
Angelborg C, Ågerup B (1975) Glycerol effects on the perilymphatic and cerebrospinal fluid pressure. Acta Otolaryngol 79: 81CrossRefGoogle Scholar
Angelborg C, Hultcrantz E, Ågerup B (1977a) The cochlear blood flow. Acta Otolaryngol 83: 92CrossRefGoogle Scholar
Angelborg C, Klockhoff I, Stahle J (1977b) Urea and hearing in patients with Menière's disease. Scand Audiol 6: 143CrossRefGoogle Scholar
Angelborg C, Klockhoff I, Larsen HC, Stahle J (1981) Hyperosmotic solutions and hearing in Menière's disease. Am J Otol (to be published)Google Scholar
Battery LL, Heyman A, Patterson JL Jr (1953) Effects of ethyl alcohol on cerebral blood flow and metabolism. JAMA 152 6: 10Google Scholar
Crone C (1965) The permeability of brain capillaries to nonelectrolytes. Acta Physiol Scand 64: 407CrossRefGoogle Scholar
Klockhoff I, Lindblom U (1967) Glycerol test in Menière's disease. Acta Otolaryngol [Suppl] 224: 449CrossRefGoogle Scholar
Larsen HC, Angelborg C, Hultcrantz E (1981a) The effect of glycerol of cochlear blood flow. ORL (to be published)Google Scholar
Larsen HC, Angelborg C, Hultcrantz E (1981) The effect of urea and mannitol on cochlear blood flow. Acta Otolaryngol (to be published)Google Scholar
Money KE, Myles WS, Hoffert BM (1974) The mechanism of positional alcohol nystagmus. J Otolaryngol 3: 302Google Scholar
Robinson A, Loeb JN (1971) Ethanol ingestion-commonest cause of elevated plasma osmolality. N Eng J Med 284: 1235CrossRefGoogle Scholar
Rubini ME, Kleeman CR, Lamdin E (1955) Studies on alcohol diuretics. I. The effect of ethyl alcohol ingestion on water, electrolytes, and acid-base metabolism. J Clin Invest 34: 439CrossRefGoogle Scholar
Weiss MH, Craig JR (1978) The influence of acute ethanol intoxication on intracranial physical dynamics. Bull Los Angeles Neurol Soc 43: 1PubMedGoogle Scholar