Thrombose des Sinus cavernosus durch craniale Mucormykose
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Thrombosis of the sinus cavernosus by cranial mucormycosis
Two days after tooth-extractions a 45-year-old diabetic woman showed a total ophthalmoplegia, chemosis and a complete anesthesia of all divisions of the right cranial nerve, without exophthalmus. The patient was thought to have a mucormycosis, but this diagnosis could not be verified by culture. Because of renal insufficiency a therapy with Amphotericin B was avoided. High doses of antibiotics decreased the cellular content of the spinal fluid. But paralysis of the seventh and eigth cranial nerve and thrombosis of A. ophthalmica followed and the patient died eight days after tooth-extractions.
The autopsy verified a cranial mucormycosis. The hyphae were present in the nasal cavity, the sinuses, throughout the soft tissues of the face, the orbit, the facial bones, the cranial nerves, in the meninges and in multiple blood vessesls with consecutive thrombosis of the sinus cavernosus and the Aa. carotis int. dextra, ophthalmica dextra and maxillaris dextra.