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Journal of Materials Science

, Volume 29, Issue 15, pp 4075–4080 | Cite as

A bioactive composite material produced by the sol-gel method

  • S. M. Jones
  • S. E. Friberg
  • J. Sjöblom
Papers

Abstract

The interaction of sol-gel derived glass/organic polymer composite gel monoliths, containing a calcium salt, with an ambient solution of simulated body fluid was investigated. These gels were aged, wetted, placed in simulated body fluid, and then observed with a scanning electron microscope. The chemical compositions of the sample and the apatite were determined by energy dispersive X-ray analysis. A calcium phosphate apatite layer was clearly observed after 7 days, as was an intermediate layer which included not only calcium and phosphate in its composition but also silicon. Calcium and phosphate were also observed to be present in the outer layer of the sample, presumably having precipitated on the external surfaces of the pores in the SiO2 network.

Keywords

Calcium SiO2 Apatite Outer Layer External Surface 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    L. L. Hench, L. L. Splinter, W. C. Allen and T. K. Greenlee, J. Biomed. Mater. Res. Symp. 2 (1972) 117.Google Scholar
  2. 2.
    B. A. Blenke, H. Bromer and K. Deutscher, Med. Ortho. Technol. 95 (1975) 144.Google Scholar
  3. 3.
    M. Jarcho, J. F. Kay, K. I. Gumer, R. H. Doremus and H. P. Drombeck, J. Bioeng. 1 (1977) 79.Google Scholar
  4. 4.
    T. Kokubo, M. Shigematsu, Y. Nagashima, M. Tashiro, T. Nakamura, T. Yamamuro and S. Higashi, Bull. Inst. Chem. Res. Kyoto Univ. 60 (1982) 260.Google Scholar
  5. 5.
    W. Vogel, W. Holland, K. Naumann and J. Gummel, J. Non-Cryst. Solids 80 (1986) 34.CrossRefGoogle Scholar
  6. 6.
    K. H. Karlsson, K. Froberg and T. Ringbom, ibid. 112 (1989) 69.CrossRefGoogle Scholar
  7. 7.
    T. Kokubo, ibid. 120 (1990) 138.CrossRefGoogle Scholar
  8. 8.
    L. L. Hench, J. Am. Ceram. Soc. 74 (1991) 1487.CrossRefGoogle Scholar
  9. 9.
    D. R. Ulrich, J. Non-Cryst. Solids 121 (1990) 465.CrossRefGoogle Scholar
  10. 10.
    A. H. Heuer, D. J. Fink, V. J. Laraia, J. L. Arias, P. D. Calvert, K. Kendell, G. L. Messing, J. Blackwell, P. C. Riecke, D. H. Thompson, A. P. Wheeler, A. Veis and A. I. Caplan, Science 255 (1992) 1098.CrossRefGoogle Scholar
  11. 11.
    W. Holland, P. Wayne, K. Naumann, J. Vogel, G. Carl, C. Jana and W. Gotz, J. Non-Cryst. Solids 129 (1991) 152.CrossRefGoogle Scholar
  12. 12.
    L. L. Hench and J. Wilson, in “Materials Research Society Symposium Proceedings”, Vol. 180, Edited By J. Brinker, D. E. Clark and D. R. Ulrich (Materials Research Society, Pittsburg, PA, 1990) p. 1061.Google Scholar
  13. 13.
    C. J. Brinker and G. W. Scherer, “Sol-Gel Science” (Academic Press, New York, 1990).Google Scholar
  14. 14.
    L. Klein (Ed.), “Sol-Gel Technology For Thin Films, Fibers, Preforms, Electronics and Specialty Shapes” (Noyes, Park Ridge, Nj, 1988).Google Scholar
  15. 15.
    L. L. Hench and J. K. West, Chem. Rev. 90 (1990) 33.CrossRefGoogle Scholar
  16. 16.
    G. W. Scherer, J. Non-Cryst. Solids 87 (1986) 199.CrossRefGoogle Scholar
  17. 17.
    Idem, Ibid. 91 (1987) 101.CrossRefGoogle Scholar
  18. 18.
    Idem, in “Materials Research Society Symposium Proceedings”, Vol. 121, Edited By J. Brinker, D. E. Clark and D. R. Ulrich (Materials Research Society, Pittsburg, PA, 1988) P. 179.Google Scholar
  19. 19.
    H. Schimdt, ibid. (Materials Research Society, Pittsburg, PA, 1984) P. 327.Google Scholar
  20. 20.
    E. J. A. Pope and J. D. Mackenzie, ibid. (Materials Research Society, Pittsburg, PA, 1986) P. 809.Google Scholar
  21. 21.
    D. Ravaine, A. Seminel, Y. Charbouillot and M. Vincens, J. Non-Cryst. Solids 82 (1986) 210.CrossRefGoogle Scholar
  22. 22.
    H. Schimdt, ibid. 112 (1989) 419.CrossRefGoogle Scholar
  23. 23.
    H. Schimdt and H. Wolter, ibid. 121 (1990) 428.CrossRefGoogle Scholar
  24. 24.
    S. Kohjiya, K. Ochiai and S. Yamashita, ibid. 119 (1990) 132.CrossRefGoogle Scholar
  25. 25.
    S. E. Friberg, C. C. Yang, M. B. Biscoglio and H. Helbig, J. Mater. Sci. Lett. 11 (1992) 1373.CrossRefGoogle Scholar
  26. 26.
    O. H. Andersson, K. H. Karlsson and K. Kangasniemi, J. Non-Cryst. Solids 119 (1990) 290.CrossRefGoogle Scholar
  27. 27.
    O. H. Andersson, G. Liu, K. H. Karlsson, L. Niemi, J. Mettinen and J. Juhanoja, J. Mater. Sci. Mater. Med. 1 (1990) 219.CrossRefGoogle Scholar
  28. 28.
    O. H. Andersson and K. H. Karlsson, J. Non-Cryst. Solids 129 (1991) 145.CrossRefGoogle Scholar
  29. 29.
    C. Ohtsuki, T. Kokubo and T. Yamamuro, ibid. 143 (1992) 84.CrossRefGoogle Scholar
  30. 30.
    C. Y. Kim, A. E. Clark and L. L. Hench, ibid. 113 (1989) 195.CrossRefGoogle Scholar
  31. 31.
    K. Ohura, T. Nakamura, T. Yamamuro, Y. Ebisawa, T. Kokubo, Y. Kotoura and M. Oka, J. Mater. Sci. Mater. Med. 3 (1992) 95.CrossRefGoogle Scholar
  32. 32.
    C. Ohtsuki, T. Kokubo and T. Yamamuro, ibid. 3 (1992) 119.CrossRefGoogle Scholar
  33. 33.
    Y. Ebisawa, T. Kokubo, K. Ohura, T. Yamamuro, ibid. 1 (1990) 239.CrossRefGoogle Scholar
  34. 34.
    R. H. Doremus, J. Non-Cryst. Solids 48 (1982) 431.CrossRefGoogle Scholar
  35. 35.
    H. Scholze, ibid. 52 (1982) 91.CrossRefGoogle Scholar
  36. 36.
    R. H. Doremus, Y. Mehrotra, W. A. Lanford and C. Burman, J. Mater. Sci. 18 (1983) 612.CrossRefGoogle Scholar
  37. 37.
    H. Dunken and R. H. Doremus, J. Non-Cryst. Solids 92 (1987) 61.CrossRefGoogle Scholar
  38. 38.
    J. C. Pouxviel and J. P. Boilot, ibid. 94 (1987) 374.CrossRefGoogle Scholar
  39. 39.
    D. W. Schaefer and K. D. Keefer, in “Materials Research Society Symposium Proceedings”, Vol. 73 (Materials Research Society, Pittsburg, PA, 1986) p. 277.Google Scholar
  40. 40.
    K. D. Keefer, ibid. P. 295.Google Scholar
  41. 41.
    C. J. Brinker, K. D. Keefer, R. A. Schaefer, R. A. Assink and B. D. Kay, J. Non-Cryst. Solids 63 (1984) 45.CrossRefGoogle Scholar
  42. 42.
    C. J. Pouxviel, J. P. Boilot, J. C. Boloiel and J. Y. Lallamand, ibid. 89 (1987) 345.CrossRefGoogle Scholar
  43. 43.
    C. J. Brinker, K. D. Keefer, D. W. Schaefer and C. S. Ashlet, ibid. 48 (1982) 47.CrossRefGoogle Scholar
  44. 44.
    H. Yang, Z. Ding and X. Xu, ibid. 112 (1989) 449.CrossRefGoogle Scholar
  45. 45.
    R. H. Assink and B. D. Kay, ibid. 99 (1988) 359.CrossRefGoogle Scholar
  46. 46.
    M. M. Walker, Ms Thesis, University of Florida, Gainsville, FL (1977).Google Scholar
  47. 47.
    C. Klein and C. S. Hurlbut, “Manual of Mineralogy” (Wiley, New York, 1977) p. 359.Google Scholar

Copyright information

© Chapman & Hall 1994

Authors and Affiliations

  • S. M. Jones
    • 1
  • S. E. Friberg
    • 1
  • J. Sjöblom
    • 2
  1. 1.Center for Advanced Material Processing, Department of ChemistryClarkson UniversityPotsdamUSA
  2. 2.Department of ChemistryUniversity of BergenBergenNorway

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