Cardiac scintigraphy was performed in six patients with a documented previous myocardial infarction, in one patient with mitral regurgitation, and in four healthy volunteers following administration of 99mTc-tris-DMPE. An intense early blood pool phase permitted gated blood pool scintigraphy and left ventricular ejection fraction calculation. A myocardial phase 12–14 h later permitted myocardial perfusion imaging. The rest myocardial perfusion image quality with 99mTc-tris-DMPE appeared to be superior to the resting image quality obtained with 99mTc-dichloro-DMPE but was inferior to the resting image quality obtained with 201Tl.
This is a preview of subscription content, log in to check access.
Buy single article
Instant access to the full article PDF.
Price includes VAT for USA
Subscribe to journal
Immediate online access to all issues from 2019. Subscription will auto renew annually.
This is the net price. Taxes to be calculated in checkout.
Atkins HL, Budinger TF, Lebowitz E, Ansari AN, Greene NW, Fairchild RG, Ellis KS (1977) Thallium-201 for medical use. Part 3: Human distribution and physical imaging properties. J Nucl Med 18:133–140
Bernard SR, Chen SM (1980) Dose to the gallbladder from a 99m-Tc labeled gallbladder scanning agent. Proceedings Third International Radiation Dosimetry Symposium, Oak Ridge, pp 546–553
Deutsch E, Bushong W, Glavan KA, Elder RC, Sodo VJ, Scholz KL, Fortman DL, Lukes SJ (1981) Heart imaging with cationic complexes of technetium. Science 214:85–86
Feller PA (1974) Computer assisted medical internal radiation dosimetry (CAMIRD). South Med J 67:1394
Gerson MC, Deutsch EA, Nishiyama H, Libson KF, Adolph RJ, Grossman LW, Sodo VJ, Fortman DL, Vanderheyden JE, Williams CC, Saenger EL (1983) Myocardial perfusion imaging with technetium-99m DMPE in man. Eur J Nucl Med 8:371–374
Grossman LW, Nishiyama H, Feller PA, Hoops RG, Sodo VJ (1980) Whole body scanning for radiopharmaceutical distribution in humans. Bureau of Radiological Health Symposium on Biological Effects, Imaging Techniques and Dosimetry of Ionizing Radiations, Proceedings. HHS Publication (FDA) 80-8126:322–327
Loevinger R, Berman M (1976) A revised scheme for calculating the absorbed dose from biologically distributed radionuclides. MIRD Pamphlet No. 1, Revised. Society of Nuclear Medicine, New York
Perez-Gonzales J, Botvinick EH, Dunn R, Rahimtoola S, Ports T, Chatterjee K, Parmley WW (1982) The late prognostic value of acute scintigraphic measurement of myocardial infarction size. Circulation 66:960–971
Silverman KJ, Becker LC, Bulkley BH, Burow RD, Mellits ED, Kallman CH, Weisfeldt ML (1980) Value of early thallium-201 scintigraphy for predicting mortality in patients with acute myocardial infarction. Circulation 61:996–1003
Sorenson JA (1971) Methods for quantitating radioactivity in vivo, by external counting. Dissertation, University of Wisconsin
Snyder WS, Ford MR, Warner GG, Watson SB (1975) “S” absorbed dose per unit cumulated activity per selected radionuclides and organs. MIRD Pamphlet No. 11, Society of Nuclear Medicine, New York
Wackers FJ, Becker AE, Samson G, Sokole EB, Van der Schoot JB, Vet AJ, Lie KI, Durrer D, Wellens H (1977) Location and size of acute transmural myocardial infarction estimated from thallium-201 scintiscans. Circulation 56:72–78
Financial support for this study was provided by the University of Cincinnati Research Council, Cincinnati, Ohio and the National Institutes of Health, Grant HL-21276, Bethesda, Maryland, USA
About this article
Cite this article
Gerson, M.C., Deutsch, E.A., Libson, K.F. et al. Myocardial scintigraphy with 99mTc-tris-DMPE in man. Eur J Nucl Med 9, 403–407 (1984). https://doi.org/10.1007/BF00295574
- Myocardial Perfusion
- Myocardial Perfusion Image
- Mitral Regurgitation
- Blood Pool
- Previous Myocardial Infarction