Different crown-gall culture strains of Crepis capillaris derived from haploid and diploid tumors were studied karyologically during the period of 18 transfers (18–20 months). The very low proportion of mitotic anomalies observed in the first transfers is in agreement with the generally accepted assumption that chromosomal changes are not involved in the initiation of tumors. However, it has been established that an intimate relationship exists between chromosome aberrations and the further development of the tumors. Morphological and physiological changes which occurred in some strains and substrains were invariably associated with cytologieal changes. The results are discussed in connection with similar phenomena described for animal tumors.
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Sacristán, M.D., Wendt-Gallitelli, M.F. Tumorous cultures of Crepis capillaris: chromosomes and growth. Chromosoma 43, 279–288 (1973). https://doi.org/10.1007/BF00294276
- Developmental Biology
- Physiological Change
- Intimate Relationship
- Chromosome Aberration
- Chromosomal Change