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No evidence for linkage between the loci for coagulation factor XIII-A and HLA

Summary

The linkage analysis between the locus for coagulation factor XIII-A (F13A) and HLA region genes (HLA-A,-C,-B) was performed. In males, the maximum of lod scores between F13A and HLA was 0.33 at θ=0.30, and in females lod scores were negative at all values of θ. The results provided no evidence for close linkage between F13A and HLA genes.

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References

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Correspondence to Keiichi Omoto.

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Nishigaki, T., Tokunaga, K., Ishii, C. et al. No evidence for linkage between the loci for coagulation factor XIII-A and HLA. Hum Genet 72, 266–267 (1986). https://doi.org/10.1007/BF00291893

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Keywords

  • Internal Medicine
  • Region Gene
  • Metabolic Disease
  • Linkage Analysis
  • Coagulation Factor