Springer Nature is making Coronavirus research free. View research | View latest news | Sign up for updates

Confirmation of linkage between the loci for HL-A and glyoxalase I

  • 25 Accesses

  • 17 Citations


Linkage analysis of 7 families with 30 children confirmed previous findings of the linkage between HL-A and GLO. Out of 28 families with 90 children the highest lod score value obtained was +8.887 (recombination fraction=0.1).

This is a preview of subscription content, log in to check access.


  1. Bender, K., Grezeschik, K. H.: Assignment of the glyoxalase I (GLO) gene to chromosome 6 using man-mouse hybrids. Third Int. Conf. on Human Gene Mapping, Boston 1975. In: Cytogenet. Cell Genet. (in press)

  2. Brand, D. U., Ray, J. G., Jr., Hare, D. B., Kayhoe, D. E., Mc. Cleland, J. D.: Preliminary trials toward standardization of leucozyte typing. In: Histocompatibility Testing 1970, p. 357. Kopenhagen: Munksgaard 1970

  3. Kömpf, J., Bissbort, S., Gussmann, S., Ritter, H.: Polymorphism of red cell glyoxalase I (EC: A new genetic marker in man. Investigation of 169 mother-child combinations. Humangenetik 27, 141–143 (1975)

  4. Maynard-Smith, S., Penrose, L. S., Smith, C. A. B.: Mathematical tables for research workers in human genetics. London: Churchill 1961

  5. Mayr, W. R., Mayr, D., Kömpf, J., Bissbort, S., Ritter, H.: Possible linkage of HL-A and GLO. Humangenetik 31, 241–242 (1976)

  6. WHO-Terminology Report in Histocompatibility Testing 1975. Copenhagen: Munksgaard (in press)

Download references

Author information

Additional information

Supported by the Deutsche Forschungsgemeinschaft.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Kömpf, J., Bissbort, S. & Schunter, F. Confirmation of linkage between the loci for HL-A and glyoxalase I. Hum Genet 32, 197–198 (1976). https://doi.org/10.1007/BF00291503

Download citation


  • Internal Medicine
  • Metabolic Disease
  • Linkage Analysis
  • Recombination Fraction