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Confirmation of linkage between the loci for HL-A and glyoxalase I

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Summary

Linkage analysis of 7 families with 30 children confirmed previous findings of the linkage between HL-A and GLO. Out of 28 families with 90 children the highest lod score value obtained was +8.887 (recombination fraction=0.1).

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References

  1. Bender, K., Grezeschik, K. H.: Assignment of the glyoxalase I (GLO) gene to chromosome 6 using man-mouse hybrids. Third Int. Conf. on Human Gene Mapping, Boston 1975. In: Cytogenet. Cell Genet. (in press)

  2. Brand, D. U., Ray, J. G., Jr., Hare, D. B., Kayhoe, D. E., Mc. Cleland, J. D.: Preliminary trials toward standardization of leucozyte typing. In: Histocompatibility Testing 1970, p. 357. Kopenhagen: Munksgaard 1970

  3. Kömpf, J., Bissbort, S., Gussmann, S., Ritter, H.: Polymorphism of red cell glyoxalase I (EC: 4.4.1.5). A new genetic marker in man. Investigation of 169 mother-child combinations. Humangenetik 27, 141–143 (1975)

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  6. WHO-Terminology Report in Histocompatibility Testing 1975. Copenhagen: Munksgaard (in press)

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Supported by the Deutsche Forschungsgemeinschaft.

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Kömpf, J., Bissbort, S. & Schunter, F. Confirmation of linkage between the loci for HL-A and glyoxalase I. Hum Genet 32, 197–198 (1976). https://doi.org/10.1007/BF00291503

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Keywords

  • Internal Medicine
  • Metabolic Disease
  • Linkage Analysis
  • Recombination Fraction