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A re-examination of the case for homology between the X and Y chromosomes of mouse and man

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Summary

Evidence is presented from the literature which suggests that in mouse and man, (1) synapsis between the X and Y is nonhomologous, (2) crossing over does not regularly occur between the X and Y, but is prevented by “precocious” desynapsis, and (3) normal disjunction of the X and Y is assured by an achiasmatic end association.

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References

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Ashley, T. A re-examination of the case for homology between the X and Y chromosomes of mouse and man. Hum Genet 67, 372–377 (1984). https://doi.org/10.1007/BF00291394

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Keywords

  • Internal Medicine
  • Assure
  • Metabolic Disease
  • Normal Disjunction