Archives of Microbiology

, Volume 156, Issue 2, pp 111–114 | Cite as

An electron microscopy study of wall expansion during Candida albicans yeast and mycelial growth using concanavalin A-ferritin labelling of mannoproteins

  • Hortensia Rico
  • Enrique Herrero
  • Fernando Miragall
  • Rafael Sentandreu
Original Papers


Depending upon growth temperature, Candida albicans can exhibit two different morphologies, a budding yeast or a mycelium. By studying the distribution of concanavalin A-ferritin particles on the cell wall surface during bud and germ tube formation, we have elucidated the way cell wall extension occurs. Both processes initially require the localized lysis of the wall in order to allow the incorporation of the newly synthesized material. Later on, the cell wall behaves as an elastic structure, allowing extension by an intosusception process and, as a consequence, cell growth.

Key words

Candida albicans Cell growth Budding Mycelium Cell wall Mannoproteins Concanavalin A 


Con A

concanavalin A


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Copyright information

© Springer-Verlag 1991

Authors and Affiliations

  • Hortensia Rico
    • 1
  • Enrique Herrero
    • 1
  • Fernando Miragall
    • 1
  • Rafael Sentandreu
    • 1
  1. 1.Departament de Microbiología, Facultat de FarmàciaUniversidat de ValènciaValènciaSpain

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