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Chromosoma

, Volume 55, Issue 1, pp 69–74 | Cite as

Random distribution of centromere regions at mitosis in cultured cells of Muntiacus muntjak

  • Raymond Mayron
  • Dwayne Wise
Article

Abstract

The manner in which centromere regions of mitotic chromosomes are distributed with respect to the age of their DNA was studied. Cells of the Indian deer, Muntiacus muntjak, were grown in the presence of bromodeoxyuridine (BrdU) for two generations and stained with the fluorescent dye Hoechst 33258. Chromatids containing “granddaughter DNA” appear dim when compared with those containing “grandparental DNA”. The frequencies of the various anaphase patterns of bright and dim centromere regions were binomially distributed, indicating random distribution of chromatids with respect to the age of their DNA templates.

Keywords

Developmental Biology Random Distribution Centromere Region Bromodeoxyuridine Mitotic Chromosome 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag 1976

Authors and Affiliations

  • Raymond Mayron
    • 1
  • Dwayne Wise
    • 1
  1. 1.Department of ZoologyDuke UniversityDurhamUSA

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