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Chromosomes in patients treated with Imuran

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Summary

Chromosome studies were performed on peripheral blood cultures in 15 patients with chronic active hepatitis, systemic lupus erythematosus or chronic glomerulonephritis before and during treatment with 1.5 to 2.5 mg/kg/day azathioprine (Imuran®). 1857 metaphase cells were examined. There was no statistically significant difference between treated and non-treated patients in chromosome aberrations.

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References

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Eberle, P., Hunstein, W. & Perings, E. Chromosomes in patients treated with Imuran. Hum Genet 6, 69–73 (1968). https://doi.org/10.1007/BF00287156

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Keywords

  • Hepatitis
  • Internal Medicine
  • Systemic Lupus Erythematosus
  • Metabolic Disease
  • Blood Culture