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Chromosomes in patients treated with Imuran

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Chromosome studies were performed on peripheral blood cultures in 15 patients with chronic active hepatitis, systemic lupus erythematosus or chronic glomerulonephritis before and during treatment with 1.5 to 2.5 mg/kg/day azathioprine (Imuran®). 1857 metaphase cells were examined. There was no statistically significant difference between treated and non-treated patients in chromosome aberrations.

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Eberle, P., Hunstein, W. & Perings, E. Chromosomes in patients treated with Imuran. Hum Genet 6, 69–73 (1968).

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  • Hepatitis
  • Internal Medicine
  • Systemic Lupus Erythematosus
  • Metabolic Disease
  • Blood Culture