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Polymorphism of human red cell glyoxalase I in six ethnic groups of China

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A total of 1242 individuals from six Chinese ethnic groups were studied with respect to the glyoxalase I polymorphism using agarose gel electrophoresis. The GLO1*1 gene frequency and the number of subjects tested in each population are as follows: Uygur 0.2466 (219), Hui 0.1621 (219), Dong 0.1866 (201), Bai 0.1921 (203), Tujia 0.1075 (200), and Maio 0.1600 (200). The differences in the GLO1 gene frequencies between some of these populations are significant.

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  1. Bagster IA, Parr CW, Welch SG (1975) Erythrocyte glyoxalase I polymorphism in an African and English population. FEBS Lett 60:336–337

  2. Bender K, Grzeschik KH (1976) Assignment of the genes for human glyoxalase I to chromosome 6 and for human esterase D to chromosome 13. Cytogenet Cell Genet 16:93–96

  3. Bender K, Frank R, Hitzeroth HW (1977) Glyoxalase I polymorphism in South African Bantu-speaking Negroids. Hum Genet 38: 223–226

  4. Ghosh AK (1977) Polymorphism of red cell glyoxalase I with special reference to South and Southeast Asia and Oceania. Hum Genet 39:91–95

  5. Goedde HW, Benkmann HG, Kriese L, Bogdanski P, Du R, Chen L, Cui M, Yuan Y, Xu J, Li S, Wang Y (1984) Population genetic studies in three Chinese minorities. Am J Phys Anthropol 64: 277–284

  6. Hashimoto M, Harada S, Omoto K (1978) Red cell glyoxalase I polymorphism in Japanese: confirmation of a low GLO1 frequency. Jinrui Idengaku Zasshi 53:139–143

  7. Kömpf J, Bissbort S, Gussmann S, Ritter H (1975) Polymorphism of red cell glyoxalase I (E.C. A new genetic marker in man. Humangenetik 27:141–143

  8. Kühnl P, Schwabenland R, Spielmann W (1977) Investigation on the polymorphism of glyoxalase I (E.C. in the population of Hessen, Germany. Hum Genet 38:99–106

  9. Martin W, Ott A (1976) Zur Darstellung der Glyoxalase I unter besonderer Berücksichtigung der Instabilität des Enzyms. Ärztl Lab 22:293–295

  10. Olaisen B, Gedde-Dahl T, Thorsberg E (1976a) Localization of the human GLO gene locus. Hum Genet 32:301–304

  11. Olaisen B, Teisberg P, Jonassen R (1976b) GLO polymrophism in Norway. Hum Hered 26:454–457

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Correspondence to Li Shizhe.

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Shizhe, L., Liqun, W. & Ruofu, D. Polymorphism of human red cell glyoxalase I in six ethnic groups of China. Hum Genet 74, 318–319 (1986). https://doi.org/10.1007/BF00282557

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  • Internal Medicine
  • Agarose
  • Ethnic Group
  • Metabolic Disease
  • Gene Frequency