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Ascertainment bias and power of procedures to estimate differences between male and female mutation rates

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References

  1. Karel ER, te Meerman GJ, ten Kate LP (1986) On the power to detect differences between male and female mutation rates for Duchenne muscular dystrophy, using classical segregation analysis and restriction fragment length polymorphisms. Am J Hum Genet 38:827–840

  2. Müller CR, Grimm T (1986) Estimation of the male to female ratio of mutation rates from the segregation of X-chromosomal DNA haplotypes in Duchenne muscular dystrophy families. Hum Genet 74: 181–183

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te Meerman, G.J., Karel, E.R. & ten Kate, L.P. Ascertainment bias and power of procedures to estimate differences between male and female mutation rates. Hum Genet 75, 296 (1987). https://doi.org/10.1007/BF00281079

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Keywords

  • Internal Medicine
  • Metabolic Disease
  • Mutation Rate
  • Ascertainment Bias
  • Female Mutation