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Brother and sister with trisomy 10p

46,XY,(22p+)mat; 46,XX,(22p+)mat


Since the usefulness of chromosome differential banding techniques has become fully established, several descriptions of chromosome 10 short arm trisomy have been published (Schleiermacher et al., 1974; Roux et al., 1974; Cantu et al., 1975; Grosse et al., 1975; Moric-Petrovic et al., 1976; Turleau et al., 1976; Johnson et al., 1977; Yunis and Lewandowski, 1977). The present report deals with a mother who is a carrier of a reciprocal translocation between chromosome 22 and 10, which has resulted in two children with a 10p trisomy.

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Correspondence to P. de Chieri.

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de Chieri, P., Spatuzza, E. & Bonich, J.M. Brother and sister with trisomy 10p. Hum Genet 45, 71–75 (1978).

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  • Internal Medicine
  • Metabolic Disease
  • Present Report
  • Reciprocal Translocation
  • Banding Technique