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Muscle provocation test. A sensitive method for discrimination between carriers and noncarriers of Duchenne muscular dystrophy

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Summary

After 40 min of strenuous exercise on a bicycle ergometer (muscle provocation test, MPT), normal women and obligate carriers showed a progressive elevation of serum creatine kinase, with a peak 8 h after exercise. The diagnostic applicability of MPT for carrier detection is demonstrated.

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References

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Correspondence to F. H. Herrmann.

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Herrmann, F.H., Spiegler, A. & Wiedemann, G. Muscle provocation test. A sensitive method for discrimination between carriers and noncarriers of Duchenne muscular dystrophy. Hum Genet 61, 102–104 (1982). https://doi.org/10.1007/BF00274196

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Keywords

  • Internal Medicine
  • Metabolic Disease
  • Creatine
  • Creatine Kinase
  • Muscular Dystrophy