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Lactose intolerance in Arabs

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Summary

A high incidence (minimum 20/26, maximum 24/26) of lactose intolerance was found in a group of adult Arab subjects. A selective reduction of intestinallactase activity was present in 4 subjects in whom a suction biopsy was performed.

Zusammenfassung

In einer Gruppe von arabischen Erwachsenen wurde eine große Häufigkeit der Lactose-Intoleranz (minimal 20/26, maximal 24/26) gefunden. Bei 4 Probanden, bei denen eine Saugbiopsie durchgeführt wurde, war die Aktivität der intestinalen Lactase erniedrigt.

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References

  1. Bolin, T. D., Davis, A. E.: Primary lactase deficiency: genetic or acquired? Amer. J. dig. Dis. 15, 679–692 (1970).

  2. Flatz, G., Rotthauwe, H. W.: Evidence against nutritional adaption of tolerance to lactose. Humangenetik 13, 118–123 (1971)

  3. Gilat, T., Malachi, E. G., Schochet, S. B.: Lactose tolerance in an Arab population. Amer. J. dig. Dis. 16, 202–203 (1971).

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  5. Rotthauwe, H. W., Flatz, G., Emons, D., Heisig, A., Kaeoplung, M.: Trennung der intestinalen ß-Galactosidasen beim lactose-intoleranten Erwachsenen durch Ultrazentrifugation im Dichtegradienten. (In preparation.)

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Additional information

This work was supported by Stiftung Volkswagenwerk and Landesamt für Forschung, Nordrhein-Westfalen.

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Rotthauwe, H.W., El-Schallah, M.O. & Flatz, G. Lactose intolerance in Arabs. Hum Genet 13, 344–346 (1971). https://doi.org/10.1007/BF00273953

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Keywords

  • Internal Medicine
  • Lactose
  • Metabolic Disease
  • Lactase
  • Selective Reduction