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A familial paracentric inversion: A short review of the current status

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Summary

We present here a familial case of a paracentric inversion in man with a short review of the literature. A paracentric inversion of chromosome 10(q11q26) was found in the amniocytes drawn for advanced maternal age. The presence of the inversion was investigated in 35 family members in three generations. No recombinants were recognized. The significance of these data for appropriate genetic counselling and possible reproductive risks is discussed.

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References

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Correspondence to Philippus A. Venter.

Additional information

Genetic Nurses, Department of Health and Welfare

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Venter, P.A., Dawson, B., Du Toit, J.L. et al. A familial paracentric inversion: A short review of the current status. Hum Genet 67, 121–125 (1984). https://doi.org/10.1007/BF00272985

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Keywords

  • Internal Medicine
  • Family Member
  • Metabolic Disease
  • Genetic Counselling
  • Short Review