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Radiation absorbed dose estimates to the embryo from some nuclear medicine procedures

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Abstract

Using the specific absorbed fractions reported by Smith and Warner, the radiation doses absorbed by the embryo in early pregnancy were calculated for various radiopharmaceuticals used in the diagnostic procedures of nuclear medicine. Radiopharmaceuticals are considered which are excreted predominantly through urine and cause the doses to the embryo to be 40%–90% higher than gonad doses. Also discussed are large differences of doses reported by various authors to the embryo by 99mTcpertechnetate.

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References

  1. Cloutier, R.J., Watson, E., Snyder, W.S.: Dose to the fetus during the first three months from gamma sources in maternal organs. In: Radiopharmaceutical Dosimetry symposium. Proc. Symp. Oak Ridge, HEW Publication (FDA) 76-8044. Rockville: U.S. Department of Health Education and Welfare 1976

  2. Dillman, L.T., von der Lage, F.C.: Radionuclide decay schemes and nuclear parameters for use in radiation dose estimation. MIRD Pamphlet No. 10. New York: Society of Nuclear Medicine 1975

  3. Ellis, R.E., Nordin, B.E.C., Tothill, P., Veall, N.: The application of the ‘ten-day rule’ in radiopharmaceutical investigations. Br. J. Radiol. 50, 200–202 (1977)

  4. Hahn, K., Brod, K.H., Wolf, R., Eissner, D.: Untersuchungen zur Strahlenbelastung des Feten bei nuklearmedizinischen Untersuchungen von Graviden. In: Nuklearmedizin. Qualitätskriterien in der Nuklearmedizin. Stuttgart-New York: F.K. Schattauer 1977

  5. Hahn, K., Wolf, R., Eissner, D.: Die Strahlenbelastung des Foeten bei nuklearmedizinischen Untersuchungen von Graviden. Vortrag beim Inter. Röntgenkongress, Rio de Janeiro 1978

  6. ICRP Publication 25: The handling, storage and disposal of nonsealed radionculides in hospitals and medical research establishments. Annals of the ICRP 1, No. 2 (1977)

  7. Lathrop, K.A., Gloria, I.V., Harper, P.V.: Response of mouse foetus to radiation from Na 99mTcO4. In: Biological and Environmental effects of low-level radiation. Proc. Symp. Chicago, Vol. II, pp. 211–221. Vienna: IAEA 1976

  8. Lathrop, K.A., Johnston, R.E., Blau, M., Rotschild, E.O.: Radiation dose to humans from 75Se-L-selenomethionine. J. Nucl. Med. 13, Suppl. No. 6 (1972)

  9. Mahon, D.F., Subramanian, G., McAfee, J.G.: Experimental comparison of radioactive agents for studies of the placenta. J. Nucl. Med. 14, 651–659 (1973)

  10. McEwan, A.C.: Patient radiation doses from radiopharmaceuticals. Report NRL 1974/3. Chritchurch: National Radiation Laboratory 1974

  11. Mian, T.A., Suzuki, H.J., Haynie, T.P., Meistrich, M.L.: Radiation damage to mouse testis cells from 99mTc-pertechnetate. J. Nucl. Med. 18, 1116–1122 (1977)

  12. MIRD/Dose estimate report No. 2. Summary of current radiation dose estimates to humans from 66Ga-, 67Ga-, 68Ga-, and 72Ga-citrate. J. Nucl. Med. 14, 755–756 (1977)

  13. MIRD/Dose estimate report No. 5. Summary of current radiation dose estimates to humans from 123I, 124I, 125I, 126I, 130I, 131I and 132I as sodium iodide. J. Nucl. Med. 16, 857–860 (1975)

  14. MIRD/Dose estimate Report No. 8. Summary of current radiation dose estimates to normal humans from 99mTc as sodium pertechnetate. J. Nucl. Med. 17, 74–77 (1976)

  15. Roedler, H.D., Kaul, A.: Radiation absorbed dose from medically administered radiopharmaceuticals. In: Biomedical dosimetry. Proc. Symp. Vienna, pp. 655–665. Vienna: IAEA 1975

  16. Sear, R.: Radioisotopes and the ‘10-day rule’. Br. J. Radiol. 47, 822 (1974)

  17. Smith, E.M., Warner, G.G.: Estimates of radiation dose to the embryo from nuclear medicine procedures. J. Nucl. Med. 17, 836–839 (1976)

  18. Subramanian, G., McAfee, J.G., Blair, R.J., Kallfelz, F.A., Thomas, F.D.: Technetium-99m-methylene disphosphonate — a superior agent for skeletal imaging: comparison with other technetium complexes. J. Nucl. Med. 16, 744–755 (1975)

  19. The developing role of short-lived radionuclides in nuclear medicine. HEW Publication (FDA) 77-8035. Rockville: U.S. Department of Health, Education and Welfare 1977

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Hušák, V., Wiedermann, M. Radiation absorbed dose estimates to the embryo from some nuclear medicine procedures. Eur J Nucl Med 5, 205–207 (1980). https://doi.org/10.1007/BF00271900

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Keywords

  • Public Health
  • Radiation
  • Radiation Dose
  • Nuclear Medicine
  • Diagnostic Procedure