Child's Nervous System

, Volume 3, Issue 6, pp 375–378 | Cite as

Delayed foreign-body reaction to silk sutures in pediatric neurosurgical patients

  • Eugene RossitchJr.
  • Dennis E. Bullard
  • W. Jerry Oakes
Original Papers


Nonabsorbable silk sutures have been a frequently used foreign material in neurosurgery. In general, they are reliable and safe with minimal bio-incompatibility. Three pediatric neurosurgical patients came to clinical attention, however, because of delayed foreign-body reactions to silk sutures. The delayed atypical presentation of these patients delayed appropriate diagnosis and therapy. In two patients, the reaction presented as a delayed inflammation 7 years following surgical suture placement. In the other patient, the reaction caused delayed recurrent shunt failures and surgical wound breakdown. These three cases are used to introduce a discussion of the delayed response of the host to foreign material and its pertinence to neurosurgery.

Key words

Foreign body reaction Silk sutures Neurosurgery 


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Copyright information

© Springer-Verlag 1987

Authors and Affiliations

  • Eugene RossitchJr.
    • 1
  • Dennis E. Bullard
    • 1
  • W. Jerry Oakes
    • 1
  1. 1.Department of Surgery, Division of NeurosurgeryDuke University Medical CenterDurhamUSA

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