Delayed foreign-body reaction to silk sutures in pediatric neurosurgical patients
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Nonabsorbable silk sutures have been a frequently used foreign material in neurosurgery. In general, they are reliable and safe with minimal bio-incompatibility. Three pediatric neurosurgical patients came to clinical attention, however, because of delayed foreign-body reactions to silk sutures. The delayed atypical presentation of these patients delayed appropriate diagnosis and therapy. In two patients, the reaction presented as a delayed inflammation 7 years following surgical suture placement. In the other patient, the reaction caused delayed recurrent shunt failures and surgical wound breakdown. These three cases are used to introduce a discussion of the delayed response of the host to foreign material and its pertinence to neurosurgery.
Key wordsForeign body reaction Silk sutures Neurosurgery
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- 4.Postlethwait RW (1969) Tissue reaction to surgical sutures. In: Dumphy JE, Van Winkle W (eds) Repair and regeneration. McGraw-Hill, New York, pp 263–285Google Scholar
- 8.Shambaugh P, Dunphy JE (1937) Postoperative wound infections and the use of silk: an experimental study. Surgery 1:379–385Google Scholar