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Paediatric meningeal tumours

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We review our experience of meningeal tumours in patients under 16 years who were treated between 1957 and 1993. These were 16 with meningiomas (median age 12 years) and 5 with poorly differentiated malignant meningeal tumours (median age 3 years). The incidence of meningeal tumours in this period was 1.62% of all CNS tumours. There were 19 supratentorial tumours (5 intraventricular), 1 tentorial and 1 cervical. Surgical excision was complete in 12 patients and incomplete in 6; in 2 patients a biopsy only was undertaken. The remaining patient had radiological diagnosis only. All 5 patients in the group with malignant poorly differentiated tumours died (median survival 5 months), confirming the aggressive nature of these lesions. Of the 16 patients with meningiomas, 4 died during follow-up but 11 of the 12 meningioma patients remaining alive had complete resections. There is a strong tendency for paediatric meningeal tumours to have a supratentorial origin and intraventricular location. The female preponderance found in adults is not evident in children. Incomplete surgical excision or focal neurological deficit at presentation was associated with poor outcome.

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  1. 1.

    Byard RW, Bourne AJ, Clark B, Hanieh A (1989) Clinicopathological and radiological features of two cases of intraventricular meningioma in childhood. Pediatr Neurosci 15:260–264

  2. 2.

    Caner H, Acikgoz B, Ozgen T, Colak A, Onol B (1992) Meningioma of the lateral ventricle. Report on six cases. Neurosurg Rev 14:303–306

  3. 3.

    Chan RC, Thompson GB (1984) Intracranial meningiomas in childhood. Surg Neurol 21:319–322

  4. 4.

    Chen HJ, Lui CC, Chen L (1986) Meningioma in the anterior III ventricle in a child. Child's Nerv Syst 2:160–161

  5. 5.

    Criscuolo GR, Symon L (1986) Intraventricular meningioma. A review of 10 cases of the National Hospital, Queen Square (1974–1985) with reference to the literature. Acta Neurochir (Wien) 83:83–91

  6. 6.

    Crouse SK, Berg BO (1972) Intracranial meningiomas in childhood and adolescence. Neurology 22:135–141

  7. 7.

    Cushing H, Eisenhardt L (1938) Meningiomas: their classification, regional behaviour, life history and surgical end results. Thomas, Springfield

  8. 8.

    Davidson GS, Hope JK (1989) Meningeal tumour of childhood Cancer 63: 1205–1210

  9. 9.

    Deen HG, Scheithauer BW, Ebersold MJ (1982) Clinical and pathological study of meningiomas of the first two decades of life. J Neurosurg 56:317–322

  10. 10.

    Diaz P, Maillo A, Morales F, Gomez-Moreta JA, Hernandez J (1990) Multiple meningiomas of the fourth ventricle in infancy. Case report. Neurosurgery 26:1057–1059

  11. 11.

    Doty JR, Schut L, Bruce DA, Sutton LN (1987) Intracranial meningiomas of childhood and adolescence. Prog Exp Tumor Res 30:247–254

  12. 12.

    Drake JM, Hoffman HJ (1991) Meningiomas in children. In: Mefty AL (ed) Meningiomas. Raven Press, pp 145–152

  13. 13.

    Ferrante L, Acqui M, Artico M, Mastronardi L, Fortuna A (1989) Paediatric intracranial meningiomas. Br J Neurosurg 3:189–196

  14. 14.

    Ferrante L, Acqui M, Artico M, Mastronardi L, Rocchi G, Fortuna A (1989) Cerebral meningiomas in children. Child's Nerv Syst 5:83–86

  15. 15.

    Germano IM, Edwards MSB, Davis RL, Schiffer D, (1994) Intracranial meningiomas of the first two decades of life. J Neurosurg 80:447–453

  16. 16.

    Goldsmith BJ, Wara WM, Wilson CB, Larson DA (1994) Postoperative irradiation for subtotally resected meningiomas. A retrospective analysis of 140 patients treated from 1967 to 1990. J Neurosurg 80:195–201

  17. 17.

    Herz DA, Shapiro K Shulman K (1980) Intracranial meningiomas of infancy, childhood and adolescence. Review of the literature and addition of 9 case reports. Child's Brain 7:43–56

  18. 18.

    Hockley AD, Hoffman HJ Hendrick EB (1977) Occipital mensenchymal tumours of infancy. Report of three cases. J Neurosurg 46:239–242

  19. 19.

    Hope JK, Armstrong DA, Babyn PS, Humphreys RR, Harwood-Nash DC, Chuang SH, Marks PV (1992) Primary meningeal tumours in children: correlation of clinical and CT findings with histologic type and prognosis. AJNR Am J Neuroradiol 13:1353–1364

  20. 20.

    Jääskeläinen J, Haltia M, Laasonen E, Walstrom T, Valtonen S (1985) The growth rate of intracranial meningiomas and its relation to histology. An analysis of 43 patients. Surg Neurol 24:165–172

  21. 21.

    Jääskeläinen J, Haltia M, Servo A (1986) Atypical and anaplastic meningiomas: radiology, surgery, radiotherapy and outcome. Surg Neurol 25: 233–242

  22. 22.

    Kolluri VRS, Reddy DR, Reddy PK, Naidu MRC, Rao SBP, Sumathi C (1987) Meningiomas in childhood. Child's Nerv Syst 3:271–273

  23. 23.

    Markwalder TM, Seiler RW, Markwalder RV, Huber P, Markwalder HM (1979) Meningioma of the anterior part of the third ventricle in a child. Surg Neurol 12:31–32

  24. 24.

    Martinez-Lage JF, Poza M, Alcaraz J, Molina E (1993) Giant meningioma of the III ventricle in a child: case report and review of the literature. Child's Nerv Syst 9:306–308

  25. 25.

    Merten DF, Gooding CA, Newton TH Malamud N (1974) Meningiomas of childhood and adolescence. J Pediatr 84:696–700

  26. 26.

    Molleston MC, Moran CJ, Roth KA, Rich KM (1994) Infantile meningioma. Pediatr Neurosurg 21:195–200

  27. 27.

    Parkin DM, Stiller CA, Draper GJ, Bieber CA, Terralini B, Young JL (1988) International incidence of childhood cancer. (IARC scientific publication no 87) IARC, Lyon, pp 20–21

  28. 28.

    Perilongo G, Sutton LN, Goldwein JW, Gushard D Schut L, Biegel JA, Rorke LB, Lange B, D'Angio GJ (1992) Childhood meningiomas. Experience in the modern imaging era. Pediatr Neurosurg 18:16–23

  29. 29.

    Renfro M, Delashaw JB, Peters K, Rhoton E (1992) Anterior third ventricle meningioma in an adolescent: a case report. Neurosurgery 31:746–750

  30. 30.

    Reusche E, Rickels E, Reale E, Stolke D (1990) Primary intracerebral sarcoma in childhood: case report with electron-microscope study. J Neurol 237:382–384

  31. 31.

    Sakaki S, Nakagawa K, Kimura H, Ohue S (1987) Intracranial meningiomas in infancy. Surg Neurol 28:51–57

  32. 32.

    Sano K, Wakai S, Ochiai C, Takakura K (1981) Characteristics of intracranial meningiomas in childhood. Child's Brain 8:96–106

  33. 33.

    Sgouros S, Walsh AR, Barber P (1994) Intraventricular malignant meningioma in a 6-year-old child. Surg Neurol 42:41–45

  34. 34.

    Stevens MCG, Cameron AH, Muir KR, Parkes SE, Reid H, Whitwell H (1991) Descriptive epidemiology of primary central nervous system tumours in children: a population-based study. Clin Oncol 3:323–329

  35. 35.

    Wilson CB (1994) Meningiomas: genetics, malignancy and the role of radiation in induction and treatment. J Neurosurg 81:666–675

  36. 36.

    Zimmerman HM (1969) Brain tumours: their incidence and classification. Ann NY Acad Sci 159:337–351

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Correspondence to C. L. Mallucci.

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Mallucci, C.L., Parkes, S.E., Barber, P. et al. Paediatric meningeal tumours. Child's Nerv Syst 12, 582–588 (1996).

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Key words

  • Malignant meningeal tumour
  • Meningioma
  • Paediatric