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Hatching requirements of dwarf tapeworm eggs (Hymenolepis nana) in relation to extraintestinal development of larval stages in mice

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Summary

It was established that cracked eggs of Hymenolepis nana would develop in the usual manner to the cysticercoid stage within 5 days when injected subcutaneously or intramuscularly into previously uninfected mice. Intestinal enzymes were not necessary to hatching stimulation. The majority of cysticercoids which developed subcutaneously in normal mice survived 3 weeks, relatively few survived 5 weeks, and there was some evidence that several may have survived as long as 8 weeks after infection. Due to the potential for extraintestinal development and survival exhibited by H. nana larval stages, it was suggested that this factor must be considered when attempting to explain the characteristically high level of infection immunity apparent with this parasite.

Zusammenfassung

Es wurde festgestellt, daß sich die Embryonen gesprengter Eier von Hymenolepis nana innerhalb von 5 Tagen in üblicher Weise zu Cysticercoiden entwickeln, wenn sie subkutan oder intramuskulär in sicher nichtinfizierte Mäuse injiziert werden. Intestinale Enzyme dürften danach also nicht zur Stimulation des Schlupfvorganges erforderlich sein. Die meisten dieser Cysticercoide überlebten 3 Wochen, relativ wenige auch 5 Wochen, einige sogar 8 Wochen. Im Hinblick auf die Fähigkeit zur extraintestinalen Entwicklung und die festgestellte Überlebenszeit wird angenommen, daß dieser Faktor berücksichtigt werden muß, wenn man den charakteristischen hohen Grad von Immunität, durch den dieser Parasit bekannt ist, zu erklären versuchen will.

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References

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Di Conza, J.J. Hatching requirements of dwarf tapeworm eggs (Hymenolepis nana) in relation to extraintestinal development of larval stages in mice. Z. F. Parasitenkunde 31, 276–281 (1968). https://doi.org/10.1007/BF00259707

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Keywords

  • Larval Stage
  • Normal Mouse
  • Usual Manner
  • Uninfected Mouse
  • Intestinal Enzyme