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Oncogenes and malignant transformation

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Abbreviations

EGF:

epidermal growth factor

PDGF:

plateletderived growth factor

LTR:

long terminal repeat (of retroviral genome)

RSV:

Rous sarcoma virus; chr.: chromosome

IgH :

immunoglobulin heavy chain

NMU:

nitrosomethylurea

DMN:

demethylnitrosamine

References

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    Albino AP et al (1984) Transforming ras genes from human melanoma: a manifestation of tumor heterogenicity? Nature 308:69–74

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    Balmain A et al (1984) Activation of the mouse cellular Harvey ras gene in chemically induced benign skin papillomas. Nature 307:658–660

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    Guerrero J et al (1984) A molecular approach to leukemogenesis: Mouse lymphomas contain an activated C-ras oncogene. Proc Natl Acad Sci 81:202–205

The following review articles contain detailed information on the subjects discussed in this paper

  1. 6.

    Bishop JM (1983) Cellular oncogenes and retroviruses. Annu Rev Biochem 52:301–354

  2. 7.

    Varmus HE (1983) The molecular genetics of cellular oncogenes. Annu Rev Genet 18:553–612

  3. 8.

    Weinberg RA (1985) The action of oncogenes in the cytoplasm and nucleus. Science 230:770–776

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van Ormondt, H., van der Eb, A.J. Oncogenes and malignant transformation. Urol. Res. 14, 119–122 (1986). https://doi.org/10.1007/BF00255828

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Keywords

  • Public Health
  • Malignant Transformation