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Retinoids and cancer

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The early and recent investigations in the field of retinoids and cancer are reviewed. The retinoids, including natural vitamin A compounds and their synthetic analogs, present a new class of substances exerting a prophylactic and a therapeutic effect both in certain experimental tumor models and in certain clinical conditions of preneoplastic and neoplastic lesions. Because of a particular physiological mechanism of action, the retinoids offer a new approach to the cancer problem, which is different from those of surgery, X-ray therapy, conventional chemotherapy, and immunotherapy.

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Bollag, W. Retinoids and cancer. Cancer Chemother. Pharmacol. 3, 207–215 (1979). https://doi.org/10.1007/BF00254733

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  • Cancer Research
  • Therapeutic Effect
  • Clinical Condition
  • Retinoid
  • Tumor Model