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Evaluation of lung epithelial permeability

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During the last few years a number of factors affecting the measurement of the rate of absorption of 99mTc-DTPA across the alveolar-capillary membrane have been identified. These have helped to provide insights into the significance of lung epithelial permeability (LEP) measurements and their potential limitations. Pulmonary absorption of 99mTc-DTPA has been studied in a variety of clinical conditions and the results are discussed.

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Correspondence to Michael I. Newhouse.

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Newhouse, M.I., Jordana, M. & Dolovich, M. Evaluation of lung epithelial permeability. Eur J Nucl Med 13, S58–S62 (1987). https://doi.org/10.1007/BF00253293

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Key words

  • Lung epithelial permeability
  • 99mTc-DTPA
  • Interstitial lung diseases
  • Bleomycin