In nine patients with different types of proximal tubulopathy and a nearly normal glomerular filtration rate a low uptake of 99mTc-DMSA in the kidneys was found. The underlying mechanism seems to be an increased urinary excretion of 99mTc-DMSA. This radiopharmaceutical might be used as a marker of proximal tubular dysfunction.
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van Luÿk, W.H.J., Ensing, G.J. & Piers, D.A. Low renal uptake of 99mTc-DMSA in patients with proximal tubular dysfunction. Eur J Nucl Med 8, 404–405 (1983). https://doi.org/10.1007/BF00253217
- Public Health
- Nuclear Medicine
- Glomerular Filtration Rate
- Underlying Mechanism