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Low renal uptake of 99mTc-DMSA in patients with proximal tubular dysfunction


In nine patients with different types of proximal tubulopathy and a nearly normal glomerular filtration rate a low uptake of 99mTc-DMSA in the kidneys was found. The underlying mechanism seems to be an increased urinary excretion of 99mTc-DMSA. This radiopharmaceutical might be used as a marker of proximal tubular dysfunction.

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Correspondence to W. H. J. van Luÿk.

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van Luÿk, W.H.J., Ensing, G.J. & Piers, D.A. Low renal uptake of 99mTc-DMSA in patients with proximal tubular dysfunction. Eur J Nucl Med 8, 404–405 (1983).

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  • Public Health
  • Filtration
  • Nuclear Medicine
  • Glomerular Filtration Rate
  • Underlying Mechanism