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Prevention of blindness in diabetic retinopathy

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Summary

Diabetic retinopathy, hitherto the most common cause of blindness in those between 30–64 years of age has become treatable. Both diabetic maculopathy and proliferative retinopathy can be treated effectively by photocoagulation. The treatment is most successful if given early, before visual loss becomes irreversible. Recently, vitrectomy with additional microsurgical techniques has been developed and shown to be effective in restoring vision to many patients blind from the complications of proliferative retinopathy.

References

  1. 1.

    Sorsby A (1972) The incidence and causes of blindness in England and Wales 1963–1968. Reports on Public Health and Medical Subjects No. 28. Her Majesty's Stationery Office, London, pp 33, 51

  2. 2.

    Kahn HA, Hiller R (1974) Blindness caused by diabetic retinopathy. Am J Ophthalmol 78: 58–67

  3. 3.

    Aiello LM, Rand RI, Briones GC, Wafai MZ, Sebestyen JG (1981) Diabetic retinopathy in Joslin clinic patients with adult onset diabetes. Ophthalmology 88: 619–623

  4. 4.

    Bodansky HJ, Cudworth AG, Whitelocke RAF, Dobree JH (1982) Diabetic retinopathy and its relation to type of diabetes: review of a retinal clinic population. Br J Ophthalmol 66: 496–499

  5. 5.

    British Multicentre Study Group (1984) Photocoagulation for diabetic maculopathy: a randomised controlled clinical trial using the xenon-arc. Diabetes 32: 1010–1016

  6. 6.

    Kohner EM (1978) Evolution and natural history of diabetic retinopathy. In: Kohner EM (ed) International ophthalmology clinics 18. Little Brown, Boston, pp 1–16

  7. 7.

    Whitelocke RAE, Kearns M, Blach RK, Hamilton AM (1979) The diabetic maculopathies. Trans Ophthalmol Soc UK 99: 314–318

  8. 8.

    Schatz H, Patz A (1976) Cystoid maculopathy in diabetes. Arch Ophthalmol 94: 761–768

  9. 9.

    Kearns M, Hamilton AM, Kohner EM (1979) Excessive permeability in diabetic maculopathy. Br J Ophthalmol 63: 487–497

  10. 10.

    Irvine AR, Norton EWD (1971) Photocoagulation for diabetic retinopathy. Am J Ophthalmol 71: 437–445

  11. 11.

    Spalter HF (1974) Photocoagulation of exudative diabetic retinopathy. Mod Probl Ophthalmol 12: 175–281

  12. 12.

    Patz A, Schatz H, Berkow JW, Gittlesohn AM, Ticho U (1973) Macular oedema an overlooked complication of diabetic retinopathy. Trans Pa Acad Ophthalmol Otolaryngol 77: 34–42

  13. 13.

    Kohner EM (1982) Retinal complications of insulin dependent (Type 1) diabetics. Minerva Endocrinol 7 (Suppl): 35–49

  14. 14.

    Kohner EM, McLeod D, Marshall J (1982) Diabetic eye disease. In: Keen H, Jarrett RJ (eds) Complications of diabetes. 2nd edn Edward Arnold, London, pp 72–75

  15. 15.

    Patz A (1978) Retinal vascular disease. New Engl J Med 298: 451–454

  16. 16.

    Hardy J, Panisset A, Marchildon A, Lanthier H (1969) Transpheroidal microsurgical selective anterior pituitary ablation a pathophysiological investigation of diabetic retinopathy. In: Goldberg MF, Fine SL (eds) Treatment of diabetic retinopathy. US Department of Health, Washington, pp 235–248

  17. 17.

    Kohner EM, Joplin GF, Blach RK, Cheng H, Fraser TR (1972) Pituitary ablation in the treatment of diabetic retinopathy. Trans Ophthalmol Soc UK 92: 79–90

  18. 18.

    Kingsley R, Ghosh GF, Lawson PM, Kohner EM (1983) Severe diabetic retinopathy in adolescents. Br J Ophthalmol 67: 73–79

  19. 19.

    Irsigler K, Kritz H, Najemnic C, Freyler H (1980) Reversal of florid proliferative diabetic retinopathy through achievement of normoglycaemia over 5 months by means of portable insulin dosage apparatus. Wien Klin Wochenschr 90: 270–276

  20. 20.

    Lawson PM, Champion MC, Canny C, Kingsley R, White M, Dupre J, Kohner EM (1982) Continuous subcutaneous insulin infusion does not prevent progression of proliferative and pre-proliferative retinopathy. Br J Ophthalmol 66: 762–766

  21. 21.

    Puklin JE, Tamborlane WV, Felig P, Genel M, Sherwin RS (1982) Influence of long-term insulin infusion pump treatment on diabetic retinopathy. Ophthalmology 84: 735–747

  22. 22.

    Patz A (1980) Studies on retinal neovascularisation (Friedenwald Lecture) Invest Ophthalmol Vis Sci 19: 1133–1138

  23. 23.

    Beetham WP, Aiello LM, Balodimos MC, Koncz L (1970) Ruby laser photocoagulation of early diabetic neovascular retinopathy. Arch Ophthalmol 83: 261–272

  24. 24.

    Okun E, Johnston GP (1969) Role of photocoagulation in the treatment of proliferative diabetic retinopathy. In: Goldberg M, Fine S (eds) Treatment of diabetic retinopathy. US Public Health Services, Washington, pp 523–536

  25. 25.

    Zweng HC, Little HL, Peabody RR (1971) Argon laser photocoagulation of diabetic retinopathy. Arch Ophthalmol 86: 395–400

  26. 26.

    Diabetic Retinopathy Study Research Group (1976) Preliminary report on the effects of photocoagulation therapy. Am J Ophthalmol 81: 380–397

  27. 27.

    Diabetic Retinopathy Study Research Group (1981) Photocoagulation treatment of proliferative diabetic retinopathy. Diabetic Retinopathy Study Research Group report No. 8. Ophthalmology 88: 583–600

  28. 28.

    British Multicentre Study Group (1977) Proliferative diabetic retinopathy treatment with xenon arc photocoagulation. Br Med J 1: 739–742

  29. 29.

    British Multicentre Study Group (1984) Photocoagulation for proliferative diabetic retinopathy: a randomised controlled clinical trial using the xenon-arc. Diabetologia 26: 109–115

  30. 30.

    L'Esperance FA Jr, Friedman EA, Mondschein LG (1983) Long term retention of vision following panretinal photocoagulation in diabetics. In: Friedman EA, L'Esperance FA Jr (eds) Diabetic renal-retinal syndrome. Grune & Stratton, New York, pp 285–300

  31. 31.

    Hercules BL, Wozencroft M, Gayed II, Lucas SB, Jaecock J (1980) Peripheral retinal ablation in the treatment of proliferative retinopathy during pregnancy. Br J Ophthalmol 64: 87–93

  32. 32.

    Patz A, Schatz H, Ryan SJ, Berkow JW, Lazarus MG (1972) Argon laser photocoagulation for treatment of advanced diabetic retinopathy. Trans Pa Acad Ophthalmol Otolaryngol 76: 984–989

  33. 33.

    Rubenstein K, Myska V (1972) Light coagulation treatment of neovascularisation of the optic disc. In: Cant S (ed) The optic nerve. Henry Kimpton, Edinburgh, pp 129–136

  34. 34.

    Aiello LM, Beetham WP, Balodimos MC, Chazan B, Bradley RF (1969) Ruby laser photocoagulation in treatment of diabetic proliferative retinopathy. In: Goldberg M, Fine S (eds) Treatment of diabetic retinopathy. US Department of Public Health, Washington, pp 437–464

  35. 35.

    Machemer R, Parel JM, Buettner H (1972) A new concept for vitreous surgery. Am J Ophthalmol 73: 1–7

  36. 36.

    Machemer R (1972) A new concept for vitreous surgery. 2. Surgical techniques and complications. Am J Ophthalmol 74: 1022–1033

  37. 37.

    Machemer R, Norton EWD (1972) A new concept for vitreous surgery. 3. Indication and results. Am J Ophthalmol 74: 1034–1056

  38. 38.

    Mandelcorn MS, Blankenship GW, Machemer R (1976) Pars plana vitrectomy for the management of severe diabetic retinopathy. Am J Ophthalmol 81: 246–253

  39. 39.

    Machemer R, Blankenship GW (1981) Vitrectomy for proliferative diabetic retinopathy associated with vitreous haemorrhage. Ophthalmology 88: 643–648

  40. 40.

    Michaels RG, Rice TA, Rice EF (1983) Vitrectomy for diabetic vitreous haemorrhage. Am J Ophthalmol 95: 12–21

  41. 41.

    Peyman GA, Huamonte FU, Goldberg MF, Sanders DR, Nagpal KC, Raichana M (1978) Four hundred consecutive pars plana vitrectomies with the vitreophage. Arch Ophthalmol 96: 45–50

  42. 42.

    Blankenship GW (1979) Pars plana vitrectomy for diabetic retinopathy: a report of 8 years experience. Mod Probl Ophthalmol 20: 376–386

  43. 43.

    Aaberg TM (1981) Pars plana vitrectomy for diabetic traction retinal detachment. Ophthalmology 88: 639–642

  44. 44.

    Charles S (1980) Vitrectomy for retinal detachment. Trans Ophthalmol Soc UK 100: 542–549

  45. 45.

    Rice TA, Michaels RG, Rice EF (1983) Vitrectomy for diabetic tracion detachment involving the macula. Am J Ophthalmol 95: 22–33

  46. 46.

    Kupfer C (1976) The diabetic retinopathy vitrectomy study. Am J Ophthalmol 81: 687–689

  47. 47.

    The Diabetic Retinopathy Vitrectomy Study (1977) Manual of Operations. The Diabetic Retinopathy Vitrectomy Study, Coordinating Centre, University of Minnesota, Minneapolis, Minnesota

  48. 48.

    Charles S, Flinn CC (1981) The natural history of diabetic extramacular traction retinal detachment. Arch Ophthalmol 99: 66–69

  49. 49.

    Barrie T, Feretis E, Leaver PK, McLeod D (1982) Closed microsurgery for diabetic traction macular detachment. Br J Ophthalmol 66: 754–758

  50. 50.

    Rand LI (1982) The early treatment diabetic retinopathy study. In: Friedman EA, L'Esperance Jr FA (eds) Diabetic renal-retinal syndrome. Grune & Stratton, New York, pp 151–170

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Kohner, E.M., Barry, P.J. Prevention of blindness in diabetic retinopathy. Diabetologia 26, 173–179 (1984). https://doi.org/10.1007/BF00252402

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Key words

  • Diabetic maculopathy
  • proliferative retinopathy
  • photocoagulation
  • vitrectomy