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Viability and ATP content of conidia of sorbic acid-sensitive and-resistant strains of Penicillium roqueforti after exposure to sorbic acid

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Conidia from two strains of Penicillium roqueforti, one sensitive and one resistant to inhibition by sorbic acid, were tested to determine how the chemical affected viability and ATP content of the spores. The minimum inhibitory concentration was less than 1,000 ppm for the sensitive strain and 3,000 ppm for the resistant strain. Exposing conidia to 6,000 ppm sorbic acid caused complete loss of viability in 1 day by those of the sensitive strain and in 4 days by those of the resistant strain. Exposure of conidia to sorbate solutions caused a rapid initial decrease in ATP content during the first few hours, followed by a more gradual decrease over the next 48–72 h. The same general trend was observed for both strains, but the resistant strain recovered some of the lost ATP following the rapid initial decrease. Results suggest that increased viability in the resistant strain may result from maintainance of ionic balance and an internal pH high enough to reduce the effectiveness of sorbic acid.

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Correspondence to Elmer H. Marth.

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Liewen, M.B., Marth, E.H. Viability and ATP content of conidia of sorbic acid-sensitive and-resistant strains of Penicillium roqueforti after exposure to sorbic acid. Appl Microbiol Biotechnol 21, 113–117 (1985). https://doi.org/10.1007/BF00252372

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  • Minimum Inhibitory Concentration
  • Inhibitory Concentration
  • General Trend
  • Penicillium
  • Gradual Decrease