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Calcium entry in rat parotid acinar cells


While it is generally accepted that Ca2+ plays an important regulatory role in the physiology of a number of non-excitable cells, the mechanisms which regulate intracellular [Ca2+ are far from well established. Ca2+ transporting mechanisms which distribute Ca2+ intracellularly as well as those which allow influx of extracellular Ca2+ are involved in mediating intracellular Ca2+ homestasis. In this paper we have described recent studies on the regulation of the Ca2+ influx system in the data, it appears that the process of Ca2+ entry is extremely complex and may involve several levels of regulation. Understanding the molecular basis of these regulatory mechanisms presents a challeging problem for future studies.

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Correspondence to Indu S. Ambudkar.

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Ambudkar, I.S., Lockwich, T., Hiramatsu, Y. et al. Calcium entry in rat parotid acinar cells. Mol Cell Biochem 114, 73–77 (1992).

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Key words

  • Ca2+ influx
  • Ca2+ mobilization
  • neurotransmitters
  • parotid gland
  • exocrine cells