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Central projections of the frontal organ of Rana pipiens, as demonstrated by the anterograde transport of horseradish peroxidase

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Summary

The central projections of the frontal organ of Rana pipiens are more widespread, and more similar to those of the epiphysis, than previously realized. Fibers labeled with horseradish peroxidase were traced to the amygdala, the epiphysis, the pretectal region, and several nuclear areas of the mesencephalic and diencephalic central gray. When peroxidase reaction product was carefully distinguished from neuromelanin by means of polarization microscopy, no unequivocally labeled cell bodies of centrifugal fibers could be found.

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References

  1. Böttger WV, Böttger EM (1973) Degenerationsstudien am Nervus pinealis von Rana esculenta L. nach stirnorgannaher und -ferner Durchtrennung. Z Zellforsch 136:365–391

  2. Dodt E (1973) The parietal eye (pineal and parietal organs) of lower vertebrates. In: Jung R (ed) Handbook of Physiology, Vol VII/3B, Central Processing of Visual Information Part B. Springer-Verlag, Berlin, pp 114–140

  3. Donley CS (1975) Color opponent slow potential interactions in the frontal organ of the frog: Rana pipiens. Vision Res 15:245–251

  4. Eldred WD, Nolte J (1978) Pineal photoreceptors: evidence for a vertebrate visual pigment with two physiologically active states. Vision Res 18:29–32

  5. Finger TE (1976) Gustatory pathways in the bullhead catfish. I. Connections of the anterior ganglion. J Comp Neurol 165:513–526

  6. Hafeez MA, Zerihun L (1974) Studies on central projections of the pineal nerve tract in rainbow trout, Salmo gairdneri Richardson, using cobalt chloride iontophoresis. Cell Tissue Res 154:485–510

  7. Herrick CJ (1917) The internal structure of the midbrain and thalamus of Necturus. J Comp Neurol 28:215–348

  8. Herrick CJ (1948) The Brain of the Tiger Salamander Ambystoma tigrinum. University of Chicago Press, Chicago

  9. Illing RB, Wässle H (1979) Visualization of the HRP reaction product using the polarization microscope. Neurosci Lett 13:7–11

  10. Kelley DB, Lieberburg I, McEwen BS, Pfaff DW (1978) Autoradiographic and biochemical studies of steroid hormone-concentrating cells in the brain of Rana pipiens. Brain Res 140:287–305

  11. Kelly DE, Smith SW (1964) Fine structure of the pineal organs of the adult frog, Rana pipiens. J Cell Biol 22:653–674

  12. Kicliter E, Ebbesson SOE (1976) Organization of the “nonolfactory” telencephalon. In: Llinás R, Precht W (eds) Frog Neurobiology, A Handbook. Springer-Verlag, Berlin, pp 946–972

  13. Kusunoki T, Ishibashi H, Masai H (1967) The distribution of monoamine oxidase and melanin pigment in the central nervous system of amphibia. J Hirnforsch 9:63–70

  14. Mensah P, Finger T (1975) Neuromelanin: a source of possible error in HRP material. Brain Res 98:183–188

  15. Mesulam MM (1976) The blue reaction product in horseradish peroxidase neurohistochemistry: incubation parameters and visibility. J Histochem Cytochem 24:1273–1280

  16. Morita Y (1971) Post-tetanic activity changes of the frog's neurosensory pineal end vesicle (Stirnorgan). Pflügers Arch 328:135–144

  17. Oksche A, von Harnack M (1965) Elektronenmikroskopische Untersuchungen an den Nervenbahnen des Pinealkomplexes von Rana esculenta L. Z Zellforsch 68:389–426

  18. Paul E (1972) Innervation und zentralnervöse Verbindungen des Frontalorgans von Rana temporaria und Rana esculenta. Faserdegeneration nach operativer Unterbrechung des Nervus pinealis. Z Zellforsch 128:504–511

  19. Paul E, Hartwig HG, Oksche A (1971) Neuronen und zentralnervöse Verbindungen des Pinealorgans der Anuren. Z Zellforsch 112:466–493

  20. Scalia F (1976) The optic pathway of the frog: nuclear organization and connections. In: Llinás R, Precht W (eds) Frog Neurobiology, A Handbook. Springer-Verlag, Berlin, pp 386–406

  21. Wake K, Ueck M, Oksche A (1974) Acetylcholinesterase-containing nerve cells in the pineal complex and subcommissural area of the frogs, Rana ridibunda and Rana esculenta. Cell Tissue Res 154:423–442

  22. Zilles K, Nickeleit V (1979) Efferent connections from the brain to the frontal organ in Rana temporaria demonstrated by labeling with horseradish peroxidase. Cell Tissue Res 196:189–192

  23. Zimmermann P, Paul E (1972) Reaktionsmuster verschiedener Mittel- und Zwischenhirnzentren von Rana temporaria L. nach Unterbrechung der Nervenbahnen des Pinealkomplexes. Z Zellforsch 128:512–537

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Author information

Correspondence to Dr. William D. Eldred.

Additional information

Supported by NIH grants GM-09181, EY-02083, and by BRSG RR-05357 awarded by the Biomedical Research Grant Program, Division of Research Resources, N.I.H.

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Eldred, W.D., Finger, T.E. & Nolte, J. Central projections of the frontal organ of Rana pipiens, as demonstrated by the anterograde transport of horseradish peroxidase. Cell Tissue Res. 211, 215–222 (1980). https://doi.org/10.1007/BF00236444

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Key words

  • Rana pipiens
  • Frontal organ
  • Pineal complex