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Central projections of the frontal organ of Rana pipiens, as demonstrated by the anterograde transport of horseradish peroxidase

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The central projections of the frontal organ of Rana pipiens are more widespread, and more similar to those of the epiphysis, than previously realized. Fibers labeled with horseradish peroxidase were traced to the amygdala, the epiphysis, the pretectal region, and several nuclear areas of the mesencephalic and diencephalic central gray. When peroxidase reaction product was carefully distinguished from neuromelanin by means of polarization microscopy, no unequivocally labeled cell bodies of centrifugal fibers could be found.

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Correspondence to Dr. William D. Eldred.

Additional information

Supported by NIH grants GM-09181, EY-02083, and by BRSG RR-05357 awarded by the Biomedical Research Grant Program, Division of Research Resources, N.I.H.

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Eldred, W.D., Finger, T.E. & Nolte, J. Central projections of the frontal organ of Rana pipiens, as demonstrated by the anterograde transport of horseradish peroxidase. Cell Tissue Res. 211, 215–222 (1980). https://doi.org/10.1007/BF00236444

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Key words

  • Rana pipiens
  • Frontal organ
  • Pineal complex