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The differential sensitivity to L-glutamate and L-aspartate of spinal interneurones and Renshaw cells

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Spinal interneurones activated with a short latency from peripheral nerves were more sensitive to L-glutamate than to L-aspartate. Renshaw cells were more sensitive to L-aspartate than to L-glutamate. These findings are consistent with the hypothesis that L-glutamate is the transmitter released by primary afferent fibres and L-aspartate is that released by spinal excitatory interneurones.

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C.J. Martin Travelling Fellow of the NH and MRC of Australia.

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Duggan, A.W. The differential sensitivity to L-glutamate and L-aspartate of spinal interneurones and Renshaw cells. Exp Brain Res 19, 522–528 (1974).

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  • L-Glutamate
  • L-aspartate
  • Sensitivity spinal interneurones
  • Renshaw cells