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Autoradiographic tracing of the cerebellar projections from the lateral reticular nucleus in the cat

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Summary

The autoradiographic technique was used for tracing the efferent fibers from the lateral reticular nucleus (LRN) in cats. The terminal fields lie within the granular layer of both the ipsi- and the contralateral cerebellar cortex. The projections are symmetrical, but more pronounced on the ipsilateral side. The main portion of LRN projects to lobuli I–V, to the rostral part of lobulus VI, the most caudal part of lobulus VII, to lobulus VIII, as well as to lobulus simplex, the medial parts of the lobulus ansiformis and to the lobulus paramedianus.

Medio-laterally arranged bands of dense mossy fiber terminations, directed rostro-caudally, lend support to an organized projection of the lateral reticulocerebellar fibers and further evidence for a division of the cerebellar cortex into longitudinal zones (Voogd et al., 1967, 1969). Evidence for a cerebellar re-representation of the LRN spinal segmental arrangement is not obvious, although it can not be excluded. The fibers to the contralateral side seem to mainly follow the course of the olivo-cerebellar fibers, crossing at brain stem levels. Following the general criteria for the identification of a terminal field, few, if any, fibers can be traced to the cerebellar nuclei and to regions outside the cerebellum.

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Abbreviations

Am:

N.ambiguus

Ans:

Lobulus ansiformis

CCT:

Cuneo-cerebellar tract

CN:

Cerebellar nuclei

CX:

N.cuneatus externus

DSCT:

Dorsal spino-cerebellar tract

fp:

Fissura prima

fpp:

Fissura prepyramidalis

FR:

Formatio reticularis

fs:

Fissura seounda

ION:

N.olivarius inferior

LRCT:

Lateral reticulo-cerebellar tract

LRN:

N.reticularis lateralis

N.N.VIII:

N.n.vestibularis

N.N.XII:

N.n.hypoglossus

Pfl:

Lobulus paraflocculus

Pmd:

Lobulus paramedianus

Si:

Lobulus simplex

SON:

N.olivarius superior

I–X:

Lobuli I–X

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Supported by grants from the Swiss National Foundation for Scientific Research Nrs. 3.823.72 and 3.124.73 and the Dr. Eric Slack-Gyr Foundation, Zürich.

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Künzle, H. Autoradiographic tracing of the cerebellar projections from the lateral reticular nucleus in the cat. Exp Brain Res 22, 255–266 (1975). https://doi.org/10.1007/BF00234768

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Key words

  • Lateral reticular nucleus
  • Mossy fibers
  • Cerebellum
  • Autoradiography