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Twitch potentiation during fatiguing exercise in the elderly: the effects of training

Summary

Twitch potentiation was studied during a fatigue paradigm involving intermittent maximum voluntary contractions (MVCs) of the tibialis anterior muscle in the elderly and in young adults. Resting twitch torques were similar between groups, but twitch potentiation was significantly greater (241% vs 166%) in the young; the recovery of the twitch after fatigue was similar between groups. Contraction time, time to peak torque and half-relaxation time were all significantly slower in the elderly. Following 12 weeks of resistance training in the elderly, there was no significant change in the twitch contractile properties at rest, but there was a significant main effect of training on the degree of twitch potentiation during the same fatigue protocol (peak potentiation 192% post-training vs 165% pre-training). These data suggest that the mechanism(s) responsible for twitch potentiation following MVCs may be influenced by both aging and training.

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References

  1. Alway SE, Hughson RL, Green HJ, Patla AE, Frank JS (1987) Twitch potentiation after fatiguing exercise in man. Eur J Appl Physiol 56:461–466

  2. Belanger AY, Quinlan J (1982) Muscle function studies in human plantar-flexor and dorsi-flexor muscles. Can J Neurol Sci 9:358–359

  3. Brown GL, von Euler US (1938) The after-effects of a tetanus on mammalian muscle. J Physiol (Lond) 93:39–60

  4. Campbell MJ, McComas AJ, Petito F (1973) Physiological changes in ageing muscles. J Neurol Neurosurg Psychiatry 36:174–182

  5. Close RI (1972) Dynamic properties of mammalian skeletal muscle. Physiol Rev 52:129–195

  6. Close R, Hoh JFY (1968) The after-effects of repetitive stimulation on the isometric twitch contraction of rat fast skeletal muscle. J Physiol (Lond) 197:461–477

  7. Frontera WR, Meredith CN, O'Reilly KP, Knuttgen HG, Evans WJ (1988) Strength conditioning in older men: skeletal muscle hypertrophy and improved function. J Appl Physiol 64:1038–1044

  8. Garner SH, Hicks AL, McComas AJ (1989) Prolongation of twitch potentiating mechanism throughout muscle fatigue and recovery. Exp Neurol 103:277–281

  9. Houston ME, Green HJ, Stull JT (1985) Myosin light chain phosphorylation and isometric twitch potentiation in intact human muscle. Pflügers Arch 403:348–352

  10. Larsson L, Sjödin B, Karlsson J (1978) Histochemical and biochemical changes in human skeletal muscle with age in sedentary males, age 22–65 years. Acta Physiol Scand 103:31–39

  11. Larsson L, Grimby G, Karlsson J (1979) Muscle strength and speed of movement in relation to age and muscle morphology. J Appl Physiol 46:451–456

  12. Lexell J, Henriksson-Larsén K, Winblad B, Sjöström M (1983) Distribution of different fibre types in human skeletal muscles: effects of aging studies in whole muscle cross sections. Muscle Nerve 6:588–595

  13. McDonagh JJM, White MJ, Davies CTM (1984) Different effects of ageing on the mechanical properties of human arm and leg muscles. Gerontology 30:49–54

  14. Palmer BM, Moore RL (1989) Myosin light chain phosphorylation and tension potentiation in mouse skeletal muscle. Am J Physiol 257: C1012–1019

  15. Persechini A, Stull JT (1984) Phosphorylation kinetics of skeletal muscle myosin and the effect of actomyosin ATPase activity. Biochemistry 23:4144–4150

  16. Petrella RJ, Cunningham DA, Vandervoort AA, Paterson DH (1989) Comparison of twitch potentiation in the gastrocnemius of young and elderly men. Eur J Appl Physiol 58:395–399

  17. Rall JA (1980) Effects of previous activity on the energetics of activation in frog skeletal muscle. J Gen Physiol 75:617–631

  18. Sica REP, McComas AJ (1971) Fast and slow twitch units in a human muscle. J Neurol Neurosurg Psychiatry 34:113–120

  19. Takamore M, Gutmann L, Shane SR (1971) Contractile properties of human skeletal muscle. Arch Neurol 25:535–546

  20. Vandervoort AA, Quinlan J, McComas AJ (1983) Twitch potentiation after voluntary contraction. Exp Neurol 81:141–152

  21. Vandervoort AA, McComas AJ (1986) Contractile changes in opposing muscles of the human ankle joint with aging. J Appl Physiol 61:361–367

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Correspondence to Audrey L. Hicks.

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Hicks, A.L., Cupido, C.M., Martin, J. et al. Twitch potentiation during fatiguing exercise in the elderly: the effects of training. Eur J Appl Physiol 63, 278–281 (1991). https://doi.org/10.1007/BF00233862

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Key words

  • Skeletal muscle
  • Twitch potentiation
  • Elderly
  • Training