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Fictive locomotion in the adult decerebrate rat

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Abstract

In adult immobilised, decerebrate rats, administration of l-3,4-dihydroxyphenylalanine, stimulation of the mesencephalic locomotor centre, or a combination of the two elicited fictive locomotor patterns in hindlimb muscle nerves. The patterns correspond closely to those observed in decerebrate animals that were free to move.

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Iles, J.F., Nicolopoulos-Stournaras, S. Fictive locomotion in the adult decerebrate rat. Exp Brain Res 109, 393–398 (1996). https://doi.org/10.1007/BF00229623

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Key words

  • Fictive locomotion
  • Mesencephalic locomotor region
  • l-Dopa
  • 5-Hydroxy-dl-tryptophan
  • Rat