Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Responses of the human auditory cortex to changes in one versus two stimulus features

  • 116 Accesses

  • 69 Citations

Abstract

Neuromagnetic responses were recorded with a 24 SQUID magnetometer in two “oddball” experiments to determine whether mismatch responses to changes in single stimulus features are additive. In experiment 1, the one feature deviants differed from standards in interstimulus interval (ISI) or frequency, and the two feature deviants in both ISI and frequence. In experiment 2, deviants differed in duration, frequency, or both. All deviants evoked a mismatch field (MMF) with sources close to each other in the supratemporal auditory cortex. Except for the ISI deviants, the MMF sources were about 1 cm anterior to the source of the 100ms response, N100m, to the standards. In the two experiments, MMFs obtained in response to the two feature deviants resembled closely the sum of MMFs in response to one feature deviants. The results suggest that the standards leave a multiple neuronal representation in the human auditory cortex. The particular neuronal traces of the representation react independently to changes in different features of sound stimuli.

This is a preview of subscription content, log in to check access.

References

  1. Csépe V, Pantev C, Hoke M, Hampson S, Ross B (1992) Evoked magnetic responses of the human auditory cortex to minor pitch changes: localization of the mismatch field. Electroencephalogr Clin Neurophysiol 84:538–548

  2. Hari R (1990) The neuromagnetic method in the study of the human auditory cortex. In: Grandori F, Hoke M, Romani GL (eds) Auditory evoked magnetic fields and potentials. (Advances in audiology, vol 6) Karger, Basel, pp 222–282

  3. Hari R, Hämäläinen M, Ilmoniemi R, Kaukoranta E, Reinikainen K, Salminen J, Alho K, Näätänen R, Sams M (1984) Responses of the primary auditory cortex to pitch changes of tone pips: neuromagnetic recordings in man. Neurosci Lett 50:127–132

  4. Hari R, Rif J, Tiihonen J, Sams M (1992) Neuromagnetic mismatch fields to single and paired tones. Electroencephalogr Clin Neurophysiol 82:152–154

  5. Kajola M, Ahlfors S, Ehnholm GJ, Hällström J, Hämäläinen MS, Ilmoniemi RJ, Kiviranta M, Knuutila J, Lounasmaa OV, Tesche CD, Vilkman V (1989) A 24 channel magnetometer for brain research. In: Williamson SJ, Hoke M, Stroink G, Kotani M (eds) Advances in biomagnetism. Plenum Press, New York, pp 673–676

  6. Kaukoranta E, Hämäläinen M, Sarvas J, Hari R (1986) Mixed and sensory nerve stimulations activate different cytoarchitectonic areas in the human primary somatosensory cortex SI. Neuromagnetic recordings and statistical considerations. Exp Brain Res 63:60–66

  7. Kaukoranta E, Sams M, Hari R, Hämäläinen M, Näätänen R (1989) Reactions of human auditory cortex to changes in tone duration. Hear Res 41:15–22

  8. Lounasmaa OV, Hari R, Joutsiniemi S-L, Hämäläinen M (1989) MultiSQUID recordings of human cerebral magnetic fields may give information about memory processes. Europhys Lett 9:603–608

  9. McEvoy L, Hari R, Imada T, Sams M (1993) Human auditory cortical mechanisms of sound localization. II. Interaural time differences at sound onset. Hear Res 67:98–109

  10. Näätänen R (1990) The role of attention in auditory information processing as indicated by event related potentials and other measures of cognitive function. Behav Brain Sci 13:201–288

  11. Näätänen R, Gaillard AWK, Mäntysalo S (1978) Early selective attention effect reinterpreted. Acta Psychol (Amst) 42:313–329

  12. Näätänen R, Sams M, Alho K, Paavilainen P, Reinikainen K, Sokolov EN (1988) Frequency and location specificity of the human vertex N1 wave. Electroencephalogr Clin Neurophysiol 69:523–531

  13. Näätänen R, Paavilainen P, Alho K, Reinikainen K, Sams M (1989) Do event related potentials reveal the mechanism of the auditory sensory memory in the human brain? Neurosci Lett 98:217–221

  14. Novak GP, Ritter W, Vaughan HGJ, Wiznitzer M (1990) Differentiation of negative event related potentials in an auditory discrimination task. Electroencephalogr Clin Neurophysiol 75:255–275

  15. Novak G, Ritter W, Vaughan HG Jr (1992a) Mismatch detection and the latency of temporal judgments. Psychophysiology 29:398–411

  16. Novak G, Ritter W, Vaughan HG Jr (1992b) The chronometry of attention modulated processing and automatic mismatch detection. Psychophysiology 29:412–430

  17. Pantev C, Lütkenhöner B, Hoke M, Lehnertz K (1986) Comparison between simultaneously recorded auditory evoked magnetic fields and potentials elicited by ipsilateral, contralateral and binaural tone burst stimulation. Audiology 25:54–61

  18. Pantev C, Hoke K, Lehnertz K, Lütkenhöner B (1989) Neuromagnetic evidence of an amplitopic organization of the human auditory cortex. Electroencephalogr Clin Neurophysiol 72:225–231

  19. Sams M (1991) Cortical responses to changes in auditory stimuli: magnetoencephalographic studies. Acta Otolaryngol (Stockh) [Suppl] 491:124–131

  20. Sams M, Hari R (1991) Magnetoencephalography (MEG) in the study of human auditory information processing. Ann NY Acad Sci 620:102–117

  21. Sams M, Hämäläinen M, Antervo A, Kaukoranta E, Reinikainen K, Hari R (1985) Cerebral neuromagnetic responses evoked by short auditory stimuli. Electroencephalogr Clin Neurophysiol 61:254–266

  22. Sams M, Kaukoranta E, Hämäläinen M, Näätänen R (1991) Cortical activity elicited by changes in auditory stimuli: different sources for the magnetic N100m and mismatch responses. Psychophysiology 28:21–29

  23. Winkler I, Paavilainen P, Näätänen R (1992) Can echoic memory store two traces simultaneously? A study of event related brain potentials. Psychophysiology 29:337–349

Download references

Author information

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Levänen, S., Hari, R., McEvoy, L. et al. Responses of the human auditory cortex to changes in one versus two stimulus features. Exp Brain Res 97, 177–183 (1993). https://doi.org/10.1007/BF00228828

Download citation

Key words

  • Evoked response
  • Magnetoencephalography
  • Feature detection
  • Mismatch
  • Reaction time
  • Human