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Intracranial extraskeletal myxoid chondrosarcoma with special reference to lamellar inclusions in the rough endoplasmic reticulum

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Abstract

An extraskeletal myxoid chondrosarcoma in the pineal region was studied by light and electron microscopy. The immunohistochemical positivity for S-100 protein, vimentin and collagen type II favored a chondrocytic origin of the tumor. In addition to the well-described ultrastructural features suggestive of a cartilagenous nature, this tumor had unusual lamellar inclusions in the rough endoplasmic reticulum. To the best of our knowledge, this is the first report of these special inclusion bodies in a myxoid chondrosarcoma.

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Sato, K., Kubota, T., Yoshida, K. et al. Intracranial extraskeletal myxoid chondrosarcoma with special reference to lamellar inclusions in the rough endoplasmic reticulum. Acta Neuropathol 86, 525–528 (1993). https://doi.org/10.1007/BF00228591

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Key words

  • Extraskeretal myxoid chondrosarcoma
  • Ultrastructure
  • Collagen type II
  • Rough endoplasmic reticulum
  • Lamellar inclusion