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The serum thymic factor (FTS)

Chemical and biological aspects

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Summary

The thymus produces a nonapeptide capable of inducing T cell surface markers and T cell functions in immature lymphoid cells. This peptide is found partly bound to a carrier protein in the circulation from where it has been isolated (hence its name of serum thymic factor (FTS)). Immunofluorescence studies using an antibody raised against synthetic FTS has shown that it is produced by the thymic epithelium. Its mode of action at the cellular level involves the binding to specific high affinity receptors.

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Pleau, J., Dardenne, M. & Bach, J. The serum thymic factor (FTS). Mol Cell Biochem 41, 67–72 (1981). https://doi.org/10.1007/BF00225298

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Keywords

  • Peptide
  • Cell Surface
  • Cell Function
  • Cellular Level
  • Surface Marker