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The hypothalamus of Lacerta sicula R.

I. A Golgi study on the caudal hypothalamus

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The posterior (caudal) hypothalamus of the lizard, Lacerta sicula R. was investigated by means of Golgi methods. The periventricular grey is formed mainly by isodendritic bipolar and multipolar neurons, while in the lateral hypothalamus a more stellate form of neuronal elements is encountered. CSF-contacting neurons are restricted to the tuberal area and to the paraventricular organ. In the latter area they are highly differentiated and endowed with laterally branched processes. The overall pattern of the lizard hypothalamus (organization of neuropil, lateral nuclei, appearance of cell clusters, morphology of the neuronal elements) represents an intermediate stage in the phylogenetic development of the hypothalamus, being more advanced than the amphibian stage.

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  1. Braak H (1968) Zur Ultrastruktur des Organon vasculosum hypothalami der Smaragdeidechse (Lacerta viridis). Z Zellforsch 84:285–303

  2. Butler AB (1973) Architectonic studies of the diencephalon of Iguana iguana (Linnaeus). J Comp Neurol 149:439–461

  3. Cruce JAF (1974) A cytoarchitectonic study of the diencephalon of the Tegu lizard, Tupinambis nigropunctatus. J Comp Neurol 153:215–227

  4. Fasolo A, Franzoni MF (1974) A Golgi study on tanycytes and liquor-contacting cells in the posterior hypothalamus of the newt. Cell Tissue Res 154:151–166

  5. Fasolo A, Franzoni MF (1977) A Golgi study of the hypothalamus of Amphibia. Neuronal typology. Cell Tissue Res 178:341–354

  6. Fasolo A, Franzoni MF (1978) Comparative account of the hypothalamus of amphibians. A neuroanatomic approach. In: Bargmann W (eds) Neurosecretion and neuroendocrine activity. evolution, structure and function. Springer-Verlag, Berlin, p 173

  7. Fasolo A, Gaudino G (1981) Immunohistochemical localization of somatostatin-like immunoreactivity in the hypothalamus of the lizard, Lacerta sicula. Gen Comp Endocrinol (in press)

  8. Fasolo A, Mazzi V, Franzoni MF (1978) A Golgi study of the hyothalamus of Actinopterygii. II. The posterior hypothalamus. Cell Tissue Res 191:433–447

  9. Fasolo A, Franzoni MF, Panzica GC, Panzica Viglietti C (1979) Neuronal pattern in the hypothalamus of submamalian vertebrates. A survey with some evolutionary notes. Neuro-Science Letters, S159

  10. Ghiara G (1963) Ricerche sulla regione tubero-infundibolare dell'ipotalamo nei Rettili. Atti Soc Peloritana Sc Fis Mat Nat IX:145–162

  11. Greenberg N, MacLean PD (1978) Behavior and neurology of lizards. US Department of Health, Education and Welfare, National Institute of Mental Health — Rockville, Maryland (USA)

  12. Marschall C (1980) Hypothalamic monoamines in lizards (Lacerta). A histofluorescence study. Cell Tissue Res 205:95–105

  13. Mazzi V, Franzoni MF, Fasolo A (1978) A Golgi study of the hypothalamus of Actinopterygii. I. The preoptic area. Cell Tissue Res 186:475–490

  14. Oksche A (1976) The neuroanatomical basis of comparative neuroendocrinology. Gen Comp Endocrinol 29:225–239

  15. Oksche A (1978a) Pattern of neuroendocrine cell complexes (subunits) in hypothalamic nuclei: Neurobiological and phylogenetic concepts. In: W Bargmann, A. Oksche, A. Polenov, B. Scharrer (eds). Neurosecretion and neuroendocrine activity. Evolution, structure and function. Springer-Verlag, Berlin Heidelberg New York pp 64–71

  16. Oksche A (1978b) Evolution, differentiation and organization of hypothalamic systems controlling reproduction. Neurobiological concepts. In: Scott DE, Kozlowski GP, Weindl A (eds) Brain-endocrine interaction. III. Neural hormones and reproduction. Karger, Basel, pp 1–15

  17. Oksche A, Zimmermann P, Oehmke HJ (1972) Morphometric studies of tubero-eminential systems controlling reproductive functions. In: Knigge KM, Scott DE, Weindl A (eds) Brain-endocrine interaction. Median eminence: structure and function. Karger, Basel, pp 142–153

  18. Prasada Rao PD, Subhedar N (1977) A cytoarchitectonic study of the hypothalamus of the lizard, Calotes versicolor. Cell Tissue Res 180:63–85

  19. Prasada Rao PD, Subhedar N, Raju PD (1981) Cytoarchitectonic pattern of the hypothalamus in the cobra, Naja naja. Cell Tissue Res 217:505–529

  20. Ramón-Moliner E (1968) The morphology of dendrites. In: Bourne HG (ed) The structure and function of nervous tissue. Vol 1. Academic Press, New York London, pp 205–265

  21. Ramón-Moliner E (1975) Specialized and generalized dendritic patterns. In: Santini M (ed) Golgi Centennial Symposium: Perspectives in neurobiology. Raven Press, New York, pp 87–100

  22. Senn DG (1968) Bau und Ontogenese von Zwischen- und Mittelhirn bei Lacerta sicula (Rafinesque). Acta Anatomica 55S:64–77

  23. Stensaas LJ, Stensaas SS (1968) Astrocytic neuroglial cells, oligodendrocytes and microgliacytes in the spinal cord of the toad. I. Light microscopy. Z Zellforsch 84:473–489

  24. Vigh B, Vigh-Teichmann I (1973) Comparative ultrastructure of the cerebrospinal fluid contacting neurons. Int Rev Cytol 35:189–252

  25. Vigh-Teichmann I, Vigh B (1974) The infundibular cerebrospinal-fluid contacting neurons. Adv. Anatomy Embryology and Cell Biology 50/2. Springer-Verlag, Berlin Heidelberg New York

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Correspondence to Prof. M. F. Franzoni.

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Franzoni, M.F., Fasolo, A. The hypothalamus of Lacerta sicula R.. Cell Tissue Res. 223, 61–71 (1982).

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Key words

  • Hypothalamus
  • Lizard (Lacerta sicula R.)
  • Golgi methods