Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Pigment architecture of the human telencephalic cortex

III. Regio praesubicularis

  • 41 Accesses

  • 14 Citations

Summary

Cortical lamination and parcellation of the human presubicular region is described with the aid of stereomicroscopical analysis of pigment preparations up to 1000 μm thick. The region can be subdivided into three major territories each of which is strongly influenced by the adjoining cortical tissue. The three subregions are:

The Presubiculum Sensu Stricto

It lies near the subiculum at its medial margin and can be subdivided into 6 areas.

The Parasubiculum

It borders on the entorhinal region and is composed of 5 areas.

The Transsubiculum

It forms a transitional zone between allocortical and isocortical fields and consists of 3 areas. The presubicular region is characterized by a conspicuous layer of small and densely packed cells which — except the marginal parts of the subiculum — does not appear outside this region. Besides this autochthonous parvopyramidal layer, the presubicular cortex is composed of “foreign” cell layers which penetrate in varying number and to a varying extent into the region from the surrounding fields. The presubicular cortex shows extensive and incessant local variations, in so far as each one of its layers is very variable in breadth. In spite of this, a reliable parcellation can be achieved when only those layers are taken into consideration whose marginal parts are clearly recognizable. Hence, the proposed parcellation is based on the changing pattern of lamination which is depicted in diagrams for easy recognition of the various areas.

This is a preview of subscription content, log in to check access.

References

  1. Braak, E.: On the fine structure of the external glial layer in the isocortex of man. Cell Tiss. Res. 157, 367–390 (1975)

  2. Braak, H.: Zur Pigmentarchitektonik der Großhirnrinde des Menschen. I. Regio entorhinalis. Z. Zellforsch. 127, 407–438 (1972a)

  3. Braak, H.: Zur Pigmentarchitektonik der Großhirnrinde des Menschen. II. Subiculum. Z. Zellforsch. 131, 235–254 (1972b)

  4. Braak, H.: On the striate area of the human isocortex. A Golgi and pigmentarchitectonic study. J. comp. Neurol. 166, 341–364 (1976)

  5. Braak, H.: The pigment architecture of the human occipital lobe. Anat. Embryol. 150, 229–250 (1977)

  6. Braak, H.: On the pigmentarchitectonics of the human telencephalic cortex. In: Architectonics of the cerebral cortex (M.A.B. Brazier, H. Petsche, eds.), pp. 137–157. New York: Raven Press 1978a

  7. Braak, H.: On magnopyramidal temporal fields in the human brain — probable morphological counterparts of Wernicke's sensory speech region. Anat. Embryol. 152, 141–169(1978b)

  8. Braak, H.: Eine ausführliche Beschreibung pigmentarchitektonischer Arbeitsverfahren. Mikroskopie (1978c, in press)

  9. Braak, H., Braak, E., Strenge, H.: Gehören die Inselneurone der Regio entorhinalis zur Klasse der Pyramiden oder der Sternzellen? Z. mikr.-anat. Forsch. 90, 1017–1031 (1976)

  10. Brodmann, K.: Beiträge zur histologischen Lokalisation der Großhirnrinde. VI: Die Cortexgliederung des Menschen J. Psychol. Neurol. (Lpz.) 10, 231–246 (1908)

  11. Brodmann, K.: Vergleichende Lokalisationslehre der Großhirnrinde. Leipzig: J.A. Barth 1909

  12. Campbell, A.W.: Histological studies on the localization of cerebral function. Cambridge: University Press 1905

  13. Economo, C. von, Koskinas, G.N.: Die Cytoarchitektonik der Hirnrinde des erwachsenen Menschen. Wien und Berlin: Springer 1925

  14. Lopes, C.A.S., Mair, W.G.P.: Ultrastructure of the outer cortex and the pia mater in man. Acta neuropath. (Berl.) 28, 79–86 (1974)

  15. Lorente de Nó, R.: Studies on the structure of the cerebral cortex. II. Continuation of the study of the ammonic system. J. Psychol. Neurol. (Lpz.) 46, 113–177 (1934)

  16. Pearse, A.G.E.: The histochemical demonstration of keratin by methods involving selective oxidation. Quart. J. micr. Sci. 92, 393–402 (1951)

  17. Ramón y Cajal, S.: Studien über die Hirnrinde des Menschen. 4. Heft: Die Riechrinde beim Menschen und Säugetier. Leipzig: Barth 1903

  18. Ramón y Cajal, S.: Histologie du système nerveux de l'homme et des vertébrés. Paris: Maloine 1909 (Madrid: Consejo superior de investigaciones cientificas. Reprinted 1952 and 1955).

  19. Rose, M.: Die sog. Riechrinde beim Menschen und beim Affen. II. Teil des “Allocortex bei Tier und Mensch”. J. Psychol. Neurol. (Lpz.) 34, 261–401 (1927)

  20. Rose, M.: Cytoarchitektonik und Myeloarchitektonik der Großhirnrinde. In: Handbuch der Neurologie (O. Bumke, O. Foerster, eds.), Vol. 1, pp. 588–778. Berlin: Springer 1935

  21. Sgonina, K.: Vergleichende Anatomie der Entorhinal-und Präsubikularregion. J. Psychol. Neurol. (Lpz.) 48, 56–163 (1937)

  22. Stephan, H.: Allocortex. In: Handbuch der mikroskopischen Anatomie des Menschen (W. Bargmann, ed.), Vol. 4/9. Berlin-Heidelberg-New York: Springer 1975

  23. Vogt, C., Vogt, O.: Allgemeinere Ergebnisse unserer Hirnforschung. J. Psychol. Neurol. (Lpz.) 25, 279–461 (1919)

  24. Wall, G.: Über die Anfärbung der Neurolipofuscine mit Aldehydfuchsinen. Histochemie 29, 155–171 (1972)

Download references

Author information

Correspondence to Prof. Dr. med. Heiko Braak.

Additional information

Supported by the Deutsche Forschungsgemeinschaft (Br 317/9). Dedicated to Prof. Dr. med. H. Leonhardt on the occasion of his 60th birthday

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Braak, H. Pigment architecture of the human telencephalic cortex. Cell Tissue Res. 190, 509–523 (1978). https://doi.org/10.1007/BF00219561

Download citation

Key words

  • Cortex cerebri (Man)
  • Allocortex
  • Presubiculum
  • Pigment architecture
  • Lipofuscin