The termination of intrafusal muscle fibres was studied in muscle spindles of the tenuissimus muscle of the Chinese hamster.
Most nuclear chain fibres terminated within the spindle capsule. The nuclear bag- and nuclear chain fibres that extended beyond the limit of the spindle capsule terminated in the endomysial connective tissue of the adjacent extrafusal fibres. Three types of intracapsular terminations were found: (1) termination on the neighbouring nuclear bag fibre, (2) termination in the periaxial space without any obvious attachment site, or (3) termination on the spindle capsule. The intrafusal fibres were tapered and longitudinal sarcolemmal invaginations were poorly developed or were completely lacking. The fibre ends were characterized by their folded basal lamina, which appeared to be mechanically reinforced by associated collagen fibrils and elastic fibres.
This is a preview of subscription content, log in to check access.
Buy single article
Instant access to the full article PDF.
Price includes VAT for USA
Subscribe to journal
Immediate online access to all issues from 2019. Subscription will auto renew annually.
This is the net price. Taxes to be calculated in checkout.
Adal MN (1969) The fine structure of the sensory region of cat muscle spindle. J Ultrastruct Res 26:332–354
Barker D (1948) The innervation of the muscle-spindle. Quart J Micr Sci 89:143–186
Barker D (1974) The morphology of muscle receptors. In: Hunt, CC (ed) Handbook of sensory physiology. Vol. III, Part 2. Muscle receptors. Springer, New York, pp 1–190
Barker D, Ip MC (1961) A study of single and tandem types of muscle spindle in the cat. Proc Roy Soc B 154:377–397
Boyd IA (1962) The structure and innervation of the nuclear bag muscle fibre system and the nuclear muscle fibre system in mammalian muscle spindles. Philos Trans B 245:81–136
Bridgman CF, Eldred E (1964) Hypothesis for a pressure-sensitive mechanism in muscle spindles. Science 143:481–482
Bridgman CF, Eldred E (1965) Intramuscular pressure changes during contraction in relation to muscle spindles. Am J Physiol 209:891–899
Bridgman CF, Swenney S, Eldred E (1966) The effects of contraction and stretch of a muscle on morphology of its spindles. Anat Rec 156:67–81
Bridgman CF, Shumpert EE, Eldred E (1969) Insertions of intrafusal fibers in muscle spindles of the cat and other mammals. Anat Rec 164:391–402
Cooper S, Daniel PM (1956) Human muscle spindles. J Physiol (Lond) 133:1–3
Cravioto H, Lockwood R (1968) Long-spacing fibrous collagen in human acoustic nerve tumors. In vivo and in vitro observations. J Ultrastruct Res 24:70–85
Desaki J, Uehara Y (1979) Evidence of branching of intrafusal muscle fibers. J Electron Microsc 28:128–130
Hanak H, Böck P (1971) Die Feinstruktur der Muskel-Sehnenverbindung von Skelett- und Herzmuskel. J Ultrastruct Res 36:68–85
Hunt CC (1974) The physiology of muscle receptors. In: Hunt CC (ed) Handbook of sensory physiology. Vol. III. Part 2. Muscle receptors. Springer, New York, pp 191–234
Ishikawa H (1965) The fine structure of myo-tendon junction in some mammalian skeletal muscles. Arch Histol Jpn 25:275–296
Korneliussen H (1973) Ultrastructure of myotendinous junctions in Myxine and rat. Specializations between the plasma membrane and the lamina densa. Z Anat Entwickl-Gesch 142:91–101
Mair WGP, Tome FMS (1972) The ultrastructue of the adult and developing human myotendinous junction. Acta Neuropathol 21:239–252
Matthews BHC (1933) Nerve endings in mammalian muscles. J Physiol (Lond) 78:1–53
Matthews BHC (1972) Mammalian muscle receptors and their central actions. Williams & Wilkins, Baltimore
Milburn A (1976) The effect of the local anaesthetic bupivacaine on the muscle spindle of rat. J Neurocytol 5:425–446
Sanes JR, Marshall LM, McMahan UJ (1978) Reinnervation of muscle fiber basal lamina after removal of myofibers. J Cell Biol 78:176–198
Thomas PK (1964a) Changes in the endoneural sheaths of peripheral myelinated nerve fibers during Wallerian degeneration. J Anat 98:175–182
Thomas PK (1964b) The deposition of collagen in relation to Schwann cell basement membrane during peripheral nerve regeneration. J Cell Biol 23:375–382
Uehara Y (1969) A comparative microanatomy of the sensory terminals of the muscle spindles, as revealed by electron microscopy. (in Japanese) Med J Osaka Univ 21:21–30
Uehara Y, Campbell GR, Burnstock G (1976) Muscle and its Innervation. An atlas of fine structure. E. Arnold, London
Vracko R, Benditt EP (1972) Basal lamina: The scaffold for ordinary cell replacement. Observation on injured skeletal muscle fibers and capillaries. J Cell Biol 55:406–419
About this article
Cite this article
Desaki, J., Uehara, Y. A fine-structural study of the termination of intrafusal muscle fibres in the Chinese hamster. Cell Tissue Res. 234, 723–733 (1983). https://doi.org/10.1007/BF00218663
- Muscle spindle
- Intrafusal fibre
- Chinese hamster