Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

A fine-structural study of the termination of intrafusal muscle fibres in the Chinese hamster

Summary

The termination of intrafusal muscle fibres was studied in muscle spindles of the tenuissimus muscle of the Chinese hamster.

Most nuclear chain fibres terminated within the spindle capsule. The nuclear bag- and nuclear chain fibres that extended beyond the limit of the spindle capsule terminated in the endomysial connective tissue of the adjacent extrafusal fibres. Three types of intracapsular terminations were found: (1) termination on the neighbouring nuclear bag fibre, (2) termination in the periaxial space without any obvious attachment site, or (3) termination on the spindle capsule. The intrafusal fibres were tapered and longitudinal sarcolemmal invaginations were poorly developed or were completely lacking. The fibre ends were characterized by their folded basal lamina, which appeared to be mechanically reinforced by associated collagen fibrils and elastic fibres.

This is a preview of subscription content, log in to check access.

References

  1. Adal MN (1969) The fine structure of the sensory region of cat muscle spindle. J Ultrastruct Res 26:332–354

  2. Barker D (1948) The innervation of the muscle-spindle. Quart J Micr Sci 89:143–186

  3. Barker D (1974) The morphology of muscle receptors. In: Hunt, CC (ed) Handbook of sensory physiology. Vol. III, Part 2. Muscle receptors. Springer, New York, pp 1–190

  4. Barker D, Ip MC (1961) A study of single and tandem types of muscle spindle in the cat. Proc Roy Soc B 154:377–397

  5. Boyd IA (1962) The structure and innervation of the nuclear bag muscle fibre system and the nuclear muscle fibre system in mammalian muscle spindles. Philos Trans B 245:81–136

  6. Bridgman CF, Eldred E (1964) Hypothesis for a pressure-sensitive mechanism in muscle spindles. Science 143:481–482

  7. Bridgman CF, Eldred E (1965) Intramuscular pressure changes during contraction in relation to muscle spindles. Am J Physiol 209:891–899

  8. Bridgman CF, Swenney S, Eldred E (1966) The effects of contraction and stretch of a muscle on morphology of its spindles. Anat Rec 156:67–81

  9. Bridgman CF, Shumpert EE, Eldred E (1969) Insertions of intrafusal fibers in muscle spindles of the cat and other mammals. Anat Rec 164:391–402

  10. Cooper S, Daniel PM (1956) Human muscle spindles. J Physiol (Lond) 133:1–3

  11. Cravioto H, Lockwood R (1968) Long-spacing fibrous collagen in human acoustic nerve tumors. In vivo and in vitro observations. J Ultrastruct Res 24:70–85

  12. Desaki J, Uehara Y (1979) Evidence of branching of intrafusal muscle fibers. J Electron Microsc 28:128–130

  13. Hanak H, Böck P (1971) Die Feinstruktur der Muskel-Sehnenverbindung von Skelett- und Herzmuskel. J Ultrastruct Res 36:68–85

  14. Hunt CC (1974) The physiology of muscle receptors. In: Hunt CC (ed) Handbook of sensory physiology. Vol. III. Part 2. Muscle receptors. Springer, New York, pp 191–234

  15. Ishikawa H (1965) The fine structure of myo-tendon junction in some mammalian skeletal muscles. Arch Histol Jpn 25:275–296

  16. Korneliussen H (1973) Ultrastructure of myotendinous junctions in Myxine and rat. Specializations between the plasma membrane and the lamina densa. Z Anat Entwickl-Gesch 142:91–101

  17. Mair WGP, Tome FMS (1972) The ultrastructue of the adult and developing human myotendinous junction. Acta Neuropathol 21:239–252

  18. Matthews BHC (1933) Nerve endings in mammalian muscles. J Physiol (Lond) 78:1–53

  19. Matthews BHC (1972) Mammalian muscle receptors and their central actions. Williams & Wilkins, Baltimore

  20. Milburn A (1976) The effect of the local anaesthetic bupivacaine on the muscle spindle of rat. J Neurocytol 5:425–446

  21. Sanes JR, Marshall LM, McMahan UJ (1978) Reinnervation of muscle fiber basal lamina after removal of myofibers. J Cell Biol 78:176–198

  22. Thomas PK (1964a) Changes in the endoneural sheaths of peripheral myelinated nerve fibers during Wallerian degeneration. J Anat 98:175–182

  23. Thomas PK (1964b) The deposition of collagen in relation to Schwann cell basement membrane during peripheral nerve regeneration. J Cell Biol 23:375–382

  24. Uehara Y (1969) A comparative microanatomy of the sensory terminals of the muscle spindles, as revealed by electron microscopy. (in Japanese) Med J Osaka Univ 21:21–30

  25. Uehara Y, Campbell GR, Burnstock G (1976) Muscle and its Innervation. An atlas of fine structure. E. Arnold, London

  26. Vracko R, Benditt EP (1972) Basal lamina: The scaffold for ordinary cell replacement. Observation on injured skeletal muscle fibers and capillaries. J Cell Biol 55:406–419

Download references

Author information

Correspondence to Junzo Desaki.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Desaki, J., Uehara, Y. A fine-structural study of the termination of intrafusal muscle fibres in the Chinese hamster. Cell Tissue Res. 234, 723–733 (1983). https://doi.org/10.1007/BF00218663

Download citation

Key words

  • Muscle spindle
  • Intrafusal fibre
  • Chinese hamster