The relationship between plasma-cholinesterase (ChE) measures and the uptake of anti-cholinesterase agents among 125 greenhouse sprayers in connection with normal working conditions were studied. An in-season ChE depression was observed indicating absorption of organophosphate (OP) or carbamate insecticides (p=0.0001). The in-season enzyme depression among sprayers, exclusively exposed to carbamates (p=0.06), probably reflects chronic percutaneous or oral uptake in the intervals between spraying by cultivating pretreated flowers. The frequency of applications (p=0.03) and the wearing of protective clothings (p=0.02) seems to be working habits, which significantly influenced the ChE activities, whereas gloves or face mask did not (p>0.05). Especially, the wearing of whole-body protective clothing (p=0.008) are of particular value in preventing percutaneous absorption.
This is a preview of subscription content, log in to check access.
Buy single article
Instant access to the full article PDF.
Price includes VAT for USA
Subscribe to journal
Immediate online access to all issues from 2019. Subscription will auto renew annually.
This is the net price. Taxes to be calculated in checkout.
Brock A, Brock V (1990) Plasma cholinesterase activity in a healthy population group with no occupational exposure to cholinesterase inhibitors: Relative influence of some factors related to normal inter-and intra-individual variations. Scand J Clin Lab Invest 50:401–408
Coye MJ, Lowe JA, Maddy KT (1986) Biological monitoring of agricultural workers exposed to pesticides: I. Cholinesterase activity determinations. J Occup Med 28:619–627
Grandjean P (1990) Skin penetration: Hazardous chemicals at work. Taylor and Francis, London
Hayes W (1982) Pesticides studied in man. Williams and Wilkins, Baltimore
International Agency for Research on Cancer (1983) Miscellaneous Pesticides, vol. 30. Monographs on the evaluation of the carcinogenic risk of chemicals to humans, Lyon
Lander F, Lings S (1991) Plasma cholinesterase variation among greenhouse workers, fruitgrowers, and slaughtermen. Br J Ind Med 48:164–166
Lander F, Pike E, Hinke K, Brock A, Nielsen JB (1991) Subclinical anti-ChE agent uptake during cultivation of greenhouse flowers. Arch Environ Contam Toxicol (in press)
Moraski RV, Nielsen AP (1985) Protective clothing and its significance to the pesticide user. In: Honeycutt RC, Zweig G, Ragsdale NN (eds) Dermal exposure related to pesticide use. American Chemical Society, Washington, DC, p 395
Nigg HN (1980) Prediction of agricultural workers safety reentry times for organophosphate insecticides. Am Ind Hyg Assoc J 41:340–344
Waldron AC (1985) The potential for applicator-worker exposure to pesticides in greenhouse operations. In: Honeycutt RC, Zweig G, Ragsdale NN (eds) Dermal exposure related to pesticide use, American Chemical Society, Washington, DC, p 311
World Health Organization (1986) Organophosphorus insecticides: A general introduction. Environmental Health Criteria 63, Geneva
About this article
Cite this article
Lander, F., Hinke, K. Indoor application of anti-cholinesterase agents and the influence of personal protection on uptake. Arch. Environ. Contam. Toxicol. 22, 163–166 (1992). https://doi.org/10.1007/BF00213280
- Waste Water
- Water Management
- Water Pollution