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Two new alleles in the tetranucleotide repeat polymorphism at the lipoprotein lipase (LPL) locus

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Summary

Two new alleles are described in the tetranucleotide polymorphism at the lipoprotein lipase (LPL) locus by using polymerase chain reaction and nondenaturing polyacrylamide gel electrophoresis.

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References

  1. Oka K, Tkalcevic GT, Stocks J, Galton DJ, Brown WV (1989) Nucleotide sequence of PvuII polymorphic site at the lipoprotein lipase gene locus. Nucleic Acids Res 17:6752

  2. Sparkes RS, Zollman S, Klisak I, Kirchgessner TG, Komaromy MC, Mohandas T, Scholtz MC, Lusis AJ (1987) Human genes involved in lipolysis of plasma lipoproteins: mapping of loci for lipoprotein to 8p22 and hepatic lipase to 15q21. Genomics 1:38–144

  3. Zuliani G, Hobbs HH (1990) Tetranucleotide repeat polymorphism in the LPL gene. Nucleic Acids Res 18:4958

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Ahn, Y.I., Kamboh, M.I. & Ferrell, R.E. Two new alleles in the tetranucleotide repeat polymorphism at the lipoprotein lipase (LPL) locus. Hum Genet 90, 184 (1992). https://doi.org/10.1007/BF00210773

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Keywords

  • Polymerase Chain Reaction
  • Internal Medicine
  • Lipase
  • Polyacrylamide
  • Metabolic Disease