An association study of restriction fragment length polymorphisms (RFLPs) in the porphobilinogen deaminase (PBGD) gene and schizophrenia was conducted. RFLPs detected by MspI, PstI, ApaLI and BstNI in intron 1 of the gene were studied in 49 patients and 79 controls. There were no significant differences between the groups in allele frequencies, genotype counts or haplotype distribution.
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Owen, M.J., Mant, R., Parfitt, E. et al. No association between RFLPs at the porphobilinogen deaminase gene and schizophrenia. Hum Genet 90, 131–132 (1992). https://doi.org/10.1007/BF00210756
- Internal Medicine
- Allele Frequency
- Metabolic Disease
- Association Study