We describe two common single-base polymorphisms of the N-acetylgalactosamine-6-sulfate sulfatase gene after StyI or StuI restriction sites. These polymorphisms were readily detected by single-strand conformation polymorphism (SSCP), using the polymerase chain reaction (PCR).
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Tomatsu, S., Fukuda, S., Uchiyama, A. et al. Polymerase chain reaction detection of two novel human N-acetylgalactosamine-6-sulfate sulfatase gene polymorphisms by single-strand conformation polymorphism analysis or by StyI and StuI cleavages. Hum Genet 95, 243–244 (1995). https://doi.org/10.1007/BF00209415
- Polymerase Chain Reaction
- Internal Medicine
- Metabolic Disease
- Restriction Site
- Gene Polymorphism