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Identification of twelve new RFLP-markers on chromosome 22q11-qter


We have previously identified and regionally localized 195 chromosome-22-specific DNA markers. We now report restriction fragment length polymorphisms detected by 9 phage markers mapped to 22q11-q12, two cosmid clones mapped to 22q12-q13 and one plasmid mapped to 22q13-qter. These markers may be useful tools for mapping disease genes such as the NF2 locus, on chromosome 22.

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Carlbom, E., Sugawa, N., Larsson, C. et al. Identification of twelve new RFLP-markers on chromosome 22q11-qter. Hum Genet 88, 135–138 (1991).

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  • Internal Medicine
  • Metabolic Disease
  • Fragment Length
  • Length Polymorphism
  • Restriction Fragment Length Polymorphism