A model study of the spatial distribution of the extracellular potentials and current densities arising from an active single skeletal muscle fiber in a cylindrical volume conductor of finite radial extent is presented. The paper examines the influence of the radius of the volume conductor,b, on the extracellular potentials and currents at different field points. The equivalent sources with respect to the extracellular potential are investigated as well. The axial source density associated with the primary and secondary sources is calculated using the expressions for the intracellular and extracellular potentials. The density of the secondary sources is a decreasing function of the radius of the conducting medium and approaches zero whenb becomes infinitely big.
This is a preview of subscription content, log in to check access.
Buy single article
Instant access to the full article PDF.
Price includes VAT for USA
Subscribe to journal
Immediate online access to all issues from 2019. Subscription will auto renew annually.
This is the net price. Taxes to be calculated in checkout.
Andreassen S, Rosenfalck A (1981) Relationship of intracellular and extracellular action potentials of skeletal muscle fibers. CRC Crit Rev Bioeng 6:267–306
Clark J, Plonsey R (1966) A mathematical evaluation of the core conductor model. Biophys J 6:95–112
Ganapathy N, Clark J (1987) Extracellular currents and potentials of the active myelinated nerve fiber. Biophys J 52:749–761
Ganapathy N, Clark J, Wilson O, Giles W (1985) Forward and inverse potential field solutions for cardiac strands of cylindrical geometry. IEEE (Inst Electr Electron Eng) Trans Biomed Eng 8:566–577
Greco EC, Clark JW, Harman TL (1977) Volume-conductor fields of the isolated axon. Math Biosci 33:235–256
Henriquez CS, Plonsey R (1990) The effect of the extracellular potential on propagation in excitable tissue. Comments Theor Biol 1:47–64
Hodgkin AL, Huxley AF (1952) A quantitative description of membrane current and its application to conduction and excitation in nerve J Physiol (London) 117:500–544
Hodgkin AL, Rushton WAH (1946) The electrical constants of crustacean nerve fiber. Proc R Soc Lond Biol Sci 133:444–479
Plonsey R (1969) Bioelectric phenomena. McGraw-Hill, New York
Plonsey R (1974) The formation of bioelectric source-field relationships in terms of surface discontinuities. J Franklin Inst 297:317–324
Rosenfalck P (1969) Intra- and extracellular potential fields of active nerve and muscle fibers. Acta Physiol Scand [Suppl] 321:1–168
Trayanova N, Henriquez C, Plonsey R, (1990) Extracellular potentials and currents of a single active fiber in a restricted volume conductor. Ann Biomed Eng (in press)
About this article
Cite this article
Trayanova, N.A. Electrical behavior of a skeletal muscle fiber in a volume conductor of finite extent. Biol. Cybern. 63, 121–125 (1990). https://doi.org/10.1007/BF00203034
- Skeletal Muscle
- Muscle Fiber
- Spatial Distribution
- Secondary Source
- Skeletal Muscle Fiber