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Correction of the published sequence for the human proteolipid protein gene

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Summary

In the human proteolipid protein gene, the base sequence of the intronic region 5′ to exon 6 was found to be 5′-ctctttcattttcctgcag-3′ and not 5′-ctctttt-cattttcctgcag-3′ as previously reported.

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References

  1. Diehl H-J, Schaich M, Budzinski R-M, Stoffel W (1986) Individual exons encode the integral membrane domains of human myelin proteolipid protein. Proc Natl Acad Sci USA 83:9807–9811

  2. Gencic S, Abuelo D, Ambler M, Hudson LD (1989) Pelizaeus-Merzbacher disease: an X-linked neurological disorder of myelin metabolism with a novel mutation in the gene encoding proteolipid protein. Am J Hum Genet 45:435–442

  3. Hudson LD, Pucketts C, Berndt J, Chan J, Gencic S (1989) Mutation of the proteolipid protein gene PLP in a human X-linked yelin disorder. Proc Natl Acad Sci USA 86:8128–8131

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Author information

Correspondence to Peter J. Bridge.

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Wilkins, P.J., D'Souza, C.R. & Bridge, P.J. Correction of the published sequence for the human proteolipid protein gene. Hum Genet 86, 617–618 (1991). https://doi.org/10.1007/BF00201552

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Keywords

  • Internal Medicine
  • Metabolic Disease
  • Protein Gene
  • Base Sequence
  • Intronic Region