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Changes of contents of CO and water in blood exposed to heat—as to a possibility of estimating pre-exposure CO content of thermally coagulated blood on the basis of its water content

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Summary

A blood sample containing CO in a glass vessel was heated in a thermostated water bath at various temperatures for varying lengths of time to compare changes in CO and water contents.

With higher temperatures and longer exposure periods the degrees of thermocoagulation advanced and the contents of CO and water decreased. At the individual temperatures examined, changes of CO and water contents showed significant correlations. However, with different temperatures regressions differed significantly. The above was considered to show that the temperature, to which a blood sample had been exposed, must be known for successful application of the water content method to estimate pre-exposure CO content of heat-exposed blood.

However, this requirement is considered difficult to be met.

Zusammenfassung

In einem offenen Glasgefäß wurde kohlenoxidhaltiges Kaninchenblut während verschiedener Zeiteinheiten und bei verschiedenen Temperaturen erhitzt. Der Verlust an Wasser und der Abfall der Kohlenoxidkonzentration wurden gemessen. Je nach der Größe der thermischen Koagulation wird der Wassergehalt und die Kohlenoxidkonzentration bei steigender Temperatur und längeren Einwirkungszeiten vermindert. Eine Korrelation zwischen den Wasser- und Kohlenoxidgehalten und den Temperaturen konnte hergestellt werden. Um den Verlust an Kohlenoxid bei Hitzeeinwirkung abzuschätzen, wäre es nötig, die Temperatur, der das Blut ausgesetzt war, zu kennen. Diese Bedingung ist jedoch nur schwer zu erfüllen.

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References

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    Yamamoto K, Kuwahara C (1980) Effect of heating on CO content in the blood. Z Rechtsmed 85:275–281

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    Miyauchi C, Sakaki K (1976) Carbon monoxide determination in postmortem heated rat blood (continued report, in Japanese). Jpn J Legal Med 30:356–360

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    Yamamoto K, Yamamoto Y, Kuwahara C, Kumabe Y (1979) Gas chromatographic determination of COHb with the use of a heated gas sampler. Jpn J Legal Med 33:685–690

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Yamamoto, K., Kuwahara, C. Changes of contents of CO and water in blood exposed to heat—as to a possibility of estimating pre-exposure CO content of thermally coagulated blood on the basis of its water content. Z Rechtsmed 87, 237–242 (1981). https://doi.org/10.1007/BF00200635

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Key word

  • Blood CO determination

Schlüsselwort

  • CO-Bestimmung