Cancer Immunology, Immunotherapy

, Volume 4, Issue 2, pp 135–137 | Cite as

C. parvum in germ-free mice

  • M. T. Scott
  • T. T. MacDonald
  • P. B. Carter
Short Communication


The effect of previous sensitization to C. parvum, by cross-reacting antigens from other bacteria, on the immunostimulatory effects of C. parvum treatment were studied in germ-free and conventional mice. It was found that the development of splenomegaly and specific delayed hypersensitivity following C. parvum injection were similar in both germ-free mice and conventional mice.


Cancer Research Immunostimulatory Effect Conventional Mouse Previous Sensitization 
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Copyright information

© Springer-Verlag 1978

Authors and Affiliations

  • M. T. Scott
    • 1
  • T. T. MacDonald
    • 1
  • P. B. Carter
    • 1
  1. 1.Trudeau Institute, Inc.Saranac LakeUSA

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