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HLA restriction of human cytotoxic T cells

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References

  1. 1.

    Allison, J.P., Walker, L.E., Russell, W.A., Pellegrino, M.A., Ferrone, S., Reisfeld, R.A., Frelinger, J.A., Silver, J.: Murine Ia and human DR antigens: homology of amino-terminal sequences. Proc. Natl. Acad. Sci. USA 75, 3953 (1978)

  2. 2.

    Askonas, B.A., Webster, R.G.: Monoclonal antibodies to the haemagglutinin and to the H-2 inhibit the cross-reactive cytotoxic T cell populations induced by influenza. Eur. J. Immunol. (in press, 1979)

  3. 3.

    Barnstable, C.J., Bodmer, W.F., Brown, G., Galfre, G., Milstein, C., Williams, A.F., Ziegler, A.: Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens — new tools for genetic analysis. Cell 14, 9 (1978)

  4. 4.

    Barnstable, C.J., Jones, E.A., Crumpton, M.J.: Isolation, structure and genetics of the HLA-A, -B, -C and -DRw (Ia) antigens. Br. Med. Bull. 34, 241 (1978)

  5. 5.

    Benacerraf, B., Germain, R.N.: The immune response genes of the major histocompatibility complex. Immunol. Rev. 38, 70 (1978)

  6. 6.

    Bevan, M.J.: The major histocompatibility complex determines susceptibility to cytotoxic T cells directed against minor histocompatibility antigens. J. Exp. Med. 142, 1349 (1975)

  7. 7.

    Bergholtz, B.O., Thorsby, E.: Macrophage dependent response of immune human T lymphocytes to PPD in vitro. Influence of HLA-D histocompatibility. Scand. J. Immunol. 6, 779 (1977)

  8. 8.

    Biddison, W.E., Doherty, P.C., Webster, R.G.: Antibody to influenza virus matrix protein detects a common antigen on the surface of cells infected with type A influenza viruses. J. Exp. Med. 146, 690 (1977)

  9. 9.

    Biddison, W.E., Shaw, S., Nelson, D.L.: Virus specificity of human influenza virus-immune cytotoxic T-cells. J. Immunol. 122, 660 (1979)

  10. 10.

    Biddison, W.E., Shaw, S.: Differences in HLA antigen recognition by human influenza virus-immune cytotoxic T-cells. J. Immunol. 122, 1705 (1979)

  11. 11.

    Bodmer, W.F.: Evolutionary significance of the HLA system. Nature 237, 139 and 183 (1972)

  12. 12.

    Bodmer, W.F., Bodmer, J.G.: Evolution and function of the HLA system. Br. Med. Bull. 34, 309 (1978)

  13. 13.

    Braciale, T.J.: Immunologic recognition of influenza virus infected cells. I. Generation of a virus strain specific and a cross-reactive population of cytotoxic T cells in the responses to type A influenza viruses of different subtypes. Cell Immunol. 33, 423 (1977)

  14. 14.

    Braciale, T.J.: Immunologic recognition of influenza virus-infected cells. II. Expression of influenza A matrix protein on the infected cell surface and its role in recognition by cross-reactive cytotoxic T cells. J. Exp. Med. 146, 673 (1977)

  15. 15.

    Brewerton, D.A., Caffrey, M., Hart, F.D., James, D.C.O., Nicholls, A., Sturrock, R.D.: Ankylosing spondylitis and HLA-27. Lancet 1, 904 (1973)

  16. 16.

    Brodensteiner, J.B., Morris, H.H., Howell, J.T., Schochet, S.S.: Chronic ECHO type V virus meningoencephalitis in X-linked hypogammaglobulinaemia: treatment with immune plasma. Neurology (Minneap.) 29, 815 (1979)

  17. 17.

    Bubbers, J.E., Chen, S., Lilly, F.: Non-random inclusion of H-2K and H-2D antigens in Friend virus particles from mice of various strains. J. Exp. Med. 147, 340 (1978)

  18. 18.

    Burakoff, S.J., Germain, R.N., Benacerraf, B.: Cross-reactive lysis of trinitrophenyl (TNP)-derivatised H-2 incompatible target cells by cytolytic T lymphocytes generated against syngeneic TNP spleen cells. J. Exp. Med. 144, 1609 (1976)

  19. 19.

    Callard, R.E.: Specific in vitro antibody response to influenza virus by human blood lymphocytes. Nature in press

  20. 20.

    Communicable Disease Surveillance Centre (Public Health Laboratory Service): Influenza in the United Kingdom, 1978–9. Br. Med. J. 2, 1299 (1979)

  21. 21.

    Dickmeiss, E., Soeberg, B., Svejgaard, A.: Human cell mediated cytotoxicity against modified target cells is restricted by HLA. Nature 270, 526 (1977)

  22. 22.

    Doherty, P.C., Blanden, R.V., Zinkernagel, R.M.: Specificity of virus-immune effector T cells for H-2K and H-2D compatible interactions: implications for H-antigen diversity. Transplant. Rev. 29, 89 (1975)

  23. 23.

    Doherty, P.C., Biddison, W.E., Bennink, J.R., Knowles, B.B.: Cytotoxic T-cell responses in mice infected with influenza and vaccinia viruses vary in magnitude with H-2 genotype. J. Exp. Med. 148, 534 (1978)

  24. 24.

    Effros, R.B., Doherty, P.C., Gerhard, W.U., Bennink, J.: Generation of both cross-reactive and virus specific T cell populations after immunisation with serologically distinct influenza A viruses. J. Exp. Med. 145, 557 (1977)

  25. 25.

    Engleman, E.G., McMichael, A.J., Batey, M.E., McDevitt, H.O.: A suppressor T cell of the mixed lymphocyte reaction in man specific for the stimulating alloantigen. Evidence that identity at HLA-D between suppressor and responder is required for suppression. J. Exp. Med. 147, 137 (1978)

  26. 26.

    Ennis, F.A., Martin, W.J., Verbonitz, M.W.: Haemagglutinin specific cytotoxic T cell response during influenza infection. J. Exp. Med. 146, 893 (1977)

  27. 27.

    Ewan, V.W., Lachmann, P.J.: Demonstration of T-cell and K-cell cytotoxicity against measles-infected cells in normal subjects, multiple sclerosis and sub-acute sclerosing panencephalitis. Clin. Exp. Immunol. 30, 22 (1977)

  28. 28.

    Fazekas de St. Growth, S., Webster, R.G.: Disquisitions on original antigenic sin. I Evidence in man. J. Exp. Med. 124, 331 (1966)

  29. 29.

    Festenstein, H., Oliver, R.T.D., Sachs, J.A., McMichael, A.J., Bodmer, W.F., Mednell, N.R.: Overall analysis of the HTC data based on clusters, patterns and antigen reports. In: Histocompatibility testing 1977, Bodmer W.F., Batchelov J.R., Bodmer J.G., Festenstein H., Morris P.J., eds., p. 115. Copenhagen: Munksgaard 1977

  30. 30.

    Forman, J., Klein, J.: Immunogenetic analysis of H-2 mutants. VI Cross-reactivity in cell-mediated lympholysis between TNP-modified cells from H-2 mutant strains. Immunogenetics 4, 183 (1977)

  31. 31.

    Forman, J., Vitetta, E.S., Hart, D.A., Klein, J.: Relationship between trinitrophenyl and H-2 antigens on trinitrophenyl modified spleen cells. I H-2 antigens on cells treated with trinitrobenzenesulphonic acid are derivatized. J. Immunol. 118, 797 (1977)

  32. 32.

    Geiger, B., Rosenthal, K.L., Klein, J., Zinkernagel, R.M., Singer, S.J.: Selective and unidirectional membrane distribution of an H-2 antigen with an antibody-clustered viral antigen: Relationship to mechanisms of cytotoxic T-cell interactions. Proc. Natl. Acad. Sci. USA 76, 4603 (1979)

  33. 33.

    Gordon, R.D., Simpson, E., Samelson, L.E.: In vitro cell mediated immune responses to male specific (HY) antigen in mice. J. Exp. Med. 142, 1108 (1975)

  34. 34.

    Goulmy, E., Termijtelen, A., Bradley, B.A., van Rood, J.J.: Y antigen killing by T-cells of women is restricted by HLA. Nature 266, 544 (1977)

  35. 35.

    Goulmy, E., Bradley, B.A., Lansbergen, Q., van Rood, J.J.: The importance of H-Y incompatibility in human organ transplantation. Transplantation 6, 315 (1978)

  36. 36.

    Goulmy, E, Hamilton, J.D., Bradley, B.A.: Anti self HLA may be clonally expressed. J. Exp. Med. 149, 545 (1979)

  37. 37.

    Greenberg, L.J., Gray, E.D., Yunis, E.J.: Association of HL-A5 and immune responsiveness in vitro to streptococcal antigens. J. Exp. Med. 141, 935 (1975)

  38. 38.

    Greenberg, S.B., Criswell, B.A., Couch, R.B.: Lymphocyte-mediated cytotoxicity against influenza virus-infected cells. An in vitro method. J. Immunol. 115, 601 (1975)

  39. 39.

    Greenberg, S.B., Six, H.R., Drake, S., Couch, R.B.: Cell cytotoxicity due to specific influenza antibody production in vitro after recent influenza antigen stimulation. Proc. Natl. Acad. Sci. USA 76, 4622 (1979)

  40. 40.

    Helenius, A., Morein, B., Fries, E., Simons, K., Robinson, P., Schirrmacher, V., Terhorst, C., Strominger, J.L.: Human (HLA-A and HLA-B) and murine (H-2K and H-2D) histocompatibility antigens are cell surface receptors for Semliki Forest virus. Proc. Natl. Acad. Sci. USA 75, 3846 (1978)

  41. 41.

    Henle, G., Henle, W., Diehl, V.: Relation of Barkitt's tumor-associated herpes-type virus to infectious mononucleosis. Proc. Natl. Acad. Sci. USA 59, 94 (1968)

  42. 42.

    Hoskins, T.W., Davies, J.R., Smith, A.J., Allechin, A., Miller, C.L., Pollock, T.M.: Influenza at Christs Hospital: March 1974. Lancet 1, 105 (1976)

  43. 43.

    Kaplan, M.M., Webster, R.G.: The epidemiology of influenza. Sci. Am. 237, 88 (1977)

  44. 44.

    Klein, J.: Biology of the mouse histocompatibility-2 complex: principles of immunogenetics applied to a single system. Berlin: Springer 1975

  45. 45.

    Klein, J.: The major histocompatibility complex of the mouse. Science 203, 516 (1979)

  46. 46.

    Kreth, H.W., ter Meulen, V.: Cell mediated cytotoxicity against measles virus in SSPE. I Enhancement by antibody. J. Immunol. 118, 291 (1977)

  47. 47.

    Kreth, H.W., ter Meulen, V., Eckert, G.: Demonstration of HLA restricted killer cells in patients with acute measles. Med. Microbiol. Immunol. (Berl.) 165, 203 (1979)

  48. 48.

    Liberti, P.A., Hackett, C.J., Askonas, B.A.: Influenza virus infection of mouse lymphoblasts alters the binding affinity of anti H-2 antibody: Requirement for viral neuraminidase. Eur. J. Immunol. (in press, 1979)

  49. 49.

    Macallum, F.O.: Hypogammaglobulinaemia in the United Kingdom. VII The role of humoral antibodies in protection against and recovery from bacterial and virus infections in hypogammaglobulinaemia. M.R.C. Spec. Rep. Ser. (London) 310, 72 (1971)

  50. 50.

    McMichael, A.J., Ting, A., Zweerink, H.J., Askonas, B.A.: HLA restriction of cell-mediated lysis of influenza virus-infected human cells. Nature 270, 524 (1977)

  51. 51.

    McMichael, A.J., Askonas, B.A.: Influenza virus-specific cytotoxic T cells in man: induction and properties of the cytotoxic cell. Eur. J. Immunol. 8, 705 (1978)

  52. 52.

    McMichael, A.J.: HLA restriction of human cytotoxic T lymphocytes specific for influenza virus. Poor recognition of virus association with HLA-A2. J. Exp. Med. 148, 1458 (1978)

  53. 53.

    Moss, D.J., Rickinson, A.B., Pope, J.H.: Long-term T cell mediated immunity to Epstein-Barr virus in man. I Complete regression of virus induced transformation in cultures of seropositive donor leucocytes. Int. J. Cancer 22, 662 (1978)

  54. 54.

    Moss, D.J., Rickinson, A.B., Pope, J.H.: Long-term T cell mediated immunity to Epstein-Barr virus in man. III Activation of cytotoxic T cells in virus infected leucocyte cultures. Int. J. Cancer 23, 618 (1979)

  55. 55.

    Munro, A., Waldmann, H.: The major histocompatibility system and the immune response. Br. Med. Bull. 34, 253 (1978)

  56. 56.

    Orr, H.T., Lancet, D., Robb, R.J., Lopez de Castro, J.A., Strominger, J.L.: The heavy chain of human histocompatibility antigen HLA-B7 contains an immunoglobulin-like region. Nature 282, 266 (1979)

  57. 57.

    Paul, W.E., Benacerraf, B.: Functional specificity of thymus dependent lymphocytes. Science 195, 1293 (1977)

  58. 58.

    Perrin, L.H., Tishon, A., Oldstone, M.B.A.: Immunologic injury in measles virus infection. III Presence and characterisation of human cytotoxic lymphocytes. J. Immunol. 118, 282 (1977)

  59. 59.

    Perrin, L.H., Zinkernagel, R.M., Oldstone, M.B.A.: Immune response in humans after vaccination with vaccinia virus: generation of a virus specific cytotoxic activity by human peripheral lymphocytes. J. Exp. Med. 146, 949 (1977)

  60. 60.

    Piazza, A., Belvedere, M.C., Bernoco, D., Conighi, C., Contu, L., Cutroni, E.S., Mattiuz, P.L., Mayr, W., Richiardi, P., Scudeller, G., Ceppellini, R.: HL-A variation in four Sardinian villages under differential selective pressure by malaria. In: Histocompatibility Testing 1972, Dausset, J., Colombani, J., eds., p. 73. Copenhagen: Munksgaard 1973

  61. 61.

    Pope, J.H.: Establishment of cell lines from peripheral leucocytes in infectious mononucleosis. Nature 216, 810 (1967)

  62. 62.

    Rickinson, A.B., Moss, D.J., Pope, J.H.: Long-term T cell mediated immunity to Epstein-Barr virus in man. II Components necessary for regression in virus infected leucocyte cultures. Int. J. Cancer 23, 610 (1979)

  63. 63.

    Royston, I., Sullivan, J.L., Periman, P.O., Perlin, E.: Cell-mediated immunity to Epstein-Barr virus-transformed lymphoblastoid cells in acute infectious mononucleosis. N. Engl. J. Med. 293, 1159 (1975)

  64. 64.

    Ryder, L.O., Andersen, E., Svejgaard, A.: HLA and disease registry, 3rd report. Copenhagen: Munksgaard 1979

  65. 65.

    Sasazuki, T., Kohno, Y., Iwamoto, I., Tanimura, M., Naito, S.: Association between an HLA haplotype and low responsiveness to tetanus toxoid in man. Nature 272, 359 (1978)

  66. 66.

    Schild, G.C. (ed.): Influenza. Br. Med. Bull. 35, 1 (1979)

  67. 67.

    Schmidt-Verhulst, A.M., Shearer, G.M.: Bifunctional major histocompatibility linked genetic regulation of cell-mediated lympholysis to trinitrophenyl-modified autologous lymphocytes. J. Exp. Med. 142, 914 (1975)

  68. 68.

    Shaw, S., Nelson, D.L., Shearer, G.M.: Human cytotoxic response in vitro to trinitrophenyl-modified autologous cells. I T-cell recognition of TNP in association with widely shared antigens. J. Immunol. 121, 281 (1978)

  69. 69.

    Shaw, S., Shearer, G.M.: Human cytotoxic response in vitro to trinitrophenyl-modified autologous cells. II Diversity of self determinants recognised in association with TNP. J. Immunol. 121, 290 (1978)

  70. 70.

    Shaw, S., Biddison, W.E.: HLA-linked genetic control of the specificity of human cytotoxic T-cell responses to influenza virus. J. Exp. Med. 149, 565 (1979)

  71. 71.

    Shearer, G.M.: Cell mediated cytotoxicity to trinitrophenyl-modified syngeneic lymphocytes. Eur. J. Immunol. 4, 527 (1974)

  72. 72.

    Sheldon, P.J., Papamichail, M., Hemsted, E.H., Holborow, E.J.: Thymic origin of atypical lymphoid cells in infectious mononucleosis. Lancet 1, 1153 (1973)

  73. 73.

    Simpson, E., Gordon, R., Taylor, M., Martin, J., Chandler, P.: Micromethods for induction and assay of mouse mixed lymphocytes reactions and cytotoxicity. Eur. J. Immunol. 5, 451 (1976)

  74. 74.

    Simpson, E., Gordon, R.D.: Responsiveness to HY antigen Ir gene complementation and target cell specificity. Immunol. Rev. 35, 59 (1977)

  75. 75.

    Springer, T.A., Kaufman, J.F., Terhorst, C., Strominger, J.L.: Purification and structural characterisation of human HLA-linked B-cell antigens. Nature 268, 213 (1977)

  76. 76.

    Stuart-Harris, C.: Epidemiology of influenza in man. Br. Med. Bull. 35, 3 (1979)

  77. 77.

    Uhr, J.W., Capra, D., Vitetta, E., Cook, R.G.: Organisation of the immune response genes. Science 206, 292 (1979)

  78. 78.

    Svedmyr, E., Jondal, M.: Cytotoxic effector cells specific for B cell lines transformed by Epstein-Barr virus are present in patients with infectious mononucleosis. Proc. Natl. Acad. Sci. USA 72, 1622 (1975)

  79. 79.

    Svedmyr, E., Klein, G., Welland, O.: The EBV-carrying β2M/HLA deficient Burkitt lymphoma line Daudi is sensitive to EBV-specific killer T-cells of mononucleosis patients. Cancer Lett. 7, 15 (1979)

  80. 80.

    Tursz, T., Fridman, W.H., Senik, A., Tsapis, A., Fellous, M.: Human virus-infected target cells lacking HLA antigens resist specific T-lymphocyte cytolysis. Nature 269, 806 (1977)

  81. 81.

    Van Leeuwen, A., Goulmy, E., van Rood, J.J.: Major histocompatibility complex-restricted antibody reactivity mainly, but not exclusively, directed against cells from male donors. J. Exp. Med. 150, 1075 (1979)

  82. 82.

    Webster, A.D., Tripp, J.H., Hayward, A.R., Dayan, A.D., Doshi, R., Macintyre, E.H., Tyrrell, D.A.: Echovirus encephalitis and myositis in primary immunoglobulindeficiency. Arch. Dis. Child 53, 33 (1978)

  83. 83.

    Wettstein, P.J., Bailey, D.W., Mobraaten, L.E., Klein, J., Frelinger, J.: T-lymphocyte response to H-2 mutants: cytotoxic effectors are Ly-1+2+. Proc. Natl. Acad. Sci. USA 76, 3455 (1979)

  84. 84.

    Wright, L.L., Levy, N.L.: Generation on infected fibroblasts of human T and non T lymphocytes with specific cytotoxicity, influenced by histocompatibility, against measles virus-infected cells. J. Immunol. 122, 2379 (1979)

  85. 85.

    Yap, K.L., Ada, G.L.: The recovery of mice from influenza A virus infection. Adoptive transfer of immunity with influenza virus specific cytotoxic T-lymphocytes recognising a common virion antigen. Scand. J. Immunol. 8, 413 (1978)

  86. 86.

    Yap, K.L., Ada, G.L., McKenzie, I.F.C.: Transfer of specific cytotoxic T-lymphocytes protects mice inoculated with influenza virus. Nature 273, 236 (1978)

  87. 87.

    Zinkernagel, R.M., Doherty, P.C.: Immunological surveillance against altered self components by sensitized T lymphocytes in lymphocytic choriomeningitis. Nature 251, 547 (1974)

  88. 88.

    Zinkernagel, R.M.: H-2 compatibility requirement for virus specific T-cell mediated cytolysis. The H-2K structure involved is coded by a single cistron defined by H-2Kb mutant mice. J. Exp. Med. 143, 437 (1976)

  89. 89.

    Zinkernagel, R.M., Callahan, G.N., Althage, A., Cooper, S., Klein, P.A., Klein, J.: On the thymus in the differentiation of “H-2 self recongition” by T cells: evidence for dual recognition? J. Exp. Med. 147, 882 (1978)

  90. 90.

    Zinkernagel, R.M., Althage, A., Cooper, S., Kreeb, G., Klein, P.A., Sefton, B., Flaherty, L., Stimpfling, J., Schreffler, D., Klein, J.: Ir-genes in H-2 regulate generation of anti-viral cytotoxic T cells. Mapping to K or D and dominance of unresponsiveness. J. Exp. Med. 148, 592 (1978)

  91. 91.

    Zinkernagel, R.M., Doherty, P.C.: Virus specific cytotoxic T cells: the role of the major histocompatibility gene complex in defining specificity and responsiveness. Adv. Immunol. (in press, 1980)

  92. 92.

    Zweerink, H.J., Courtneidge, S.A., Skehel, J.J., Crumpton, M.J., Askonas, B.A.: Cytotoxic T cells kill influenza virus infected cells but do not distinguish between serologically distinct A viruses. Nature 267, 354 (1977)

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McMichael, A.J. HLA restriction of human cytotoxic T cells. Springer Semin Immunopathol 3, 3–22 (1980). https://doi.org/10.1007/BF00199923

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